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Diabetes & Endocrinology
Meta-analysis
Tirzepatide improves patient-reported physical function in adults with overweight or obesity
Tirzepatide may improve physical function for adults with overweight or obesity
A meta-analysis of 4,531 participants found that once-weekly tirzepatide 10 or 15 mg significantly improved physical function scores compare…
Adults with overweight or obesity taking tirzepatide reported better physical function scores on two questionnaires compared to those taking…
Apr 2, 2026
Diabetes & Endocrinology
Meta-analysis
Network meta-analysis compares exercise types for insulin resistance in youth with overweight or obesity
Which exercise works best for insulin resistance in kids with extra weight?
A network meta-analysis of 63 RCTs involving 3,286 children and adolescents with overweight or obesity compared exercise modalities.
For kids with extra weight, short bursts of intense exercise best lower insulin levels, while mixing cardio and weights works best for dropp…
Apr 2, 2026
Nutrition & Obesity Medicine
RCT
Phase 1 trial of once-weekly eloralintide shows weight reduction in obesity over 12 weeks
Can a new weekly injection help people lose weight? Early results show promise
A Phase 1 randomised controlled trial in 100 participants with obesity or overweight found that once-weekly subcutaneous eloralintide result…
A new weekly shot helped people with obesity lose between 2.6% and 11.3% of their body weight in early safety testing, though larger studies…
Apr 2, 2026
Nutrition & Obesity Medicine
Meta-analysis
Bariatric surgery associated with lower cardiovascular risks than GLP-1RA therapy in adults with obesity
Study finds bariatric surgery linked to lower heart risks than GLP-1 drugs in adults with obesity
A meta-analysis of observational studies including 39,569 adults with obesity found bariatric surgery was associated with lower risks of mor…
Adults with obesity who had bariatric surgery faced lower risks of death and heart failure than those taking GLP-1 drugs like Wegovy.
Apr 2, 2026
Diabetes & Endocrinology
Meta-analysis
GLP-1RA use associated with lower obesity-related cancer risk in meta-analysis of adults with T2DM/obesity
Large review finds link between GLP-1 drugs and lower obesity-related cancer risk
A systematic review and meta-analysis of 3,960,974 adults with type 2 diabetes and/or obesity found GLP-1RA use was associated with a signif…
A large review of studies involving nearly 4 million adults with type 2 diabetes or obesity found that using GLP-1 receptor agonists was ass…
Apr 2, 2026
Infectious Disease
Sys. Review
Systematic review maps gut microbiome–epigenetic crosstalk in obesity and type 2 diabetes
What's happening in your gut that might affect your weight and blood sugar?
A systematic review and bibliometric analysis of over 1,100 documents identified three major epigenetic domains involved in gut microbiome c…
Gut bacteria changes linked to obesity and type 2 diabetes may influence genetic switches, with research in this area growing nearly 28% ann…
Frontiers
Apr 1, 2026
Diabetes & Endocrinology
RCT
Mediterranean lifestyle intervention reduces BMI, fat mass in preschool girls at risk of obesity
Could a Mediterranean lifestyle help preschool girls at risk of obesity? A new study suggests it might
In a 12-month RCT of 206 preschoolers at risk of obesity, a Mediterranean lifestyle intervention (diet, physical activity) significantly red…
A Mediterranean lifestyle improved body fat and BMI for preschool girls at risk of obesity, but the same healthy habits did not help boys in…
Mar 30, 2026