Propofol-first sequence reduces hypoxemia in obese patients undergoing gastroscopy
Giving anesthesia in a new order cuts oxygen risk for obese patients
This single-center RCT compared propofol-first versus remifentanil-first sedation sequences in obese patients undergoing gastroscopy. The pr…
A new drug sequence cuts low oxygen events by nearly half in obese patients getting gastroscopy sedation.
Intensive lifestyle intervention improves health-related quality of life in patients with obesity
Greater weight loss linked to better quality of life in obesity patients
This randomized controlled trial enrolled 803 patients with obesity across eighteen primary care clinics.
A large trial shows that losing more weight is associated with better quality of life, though some racial differences were noted.
Semaglutide reduces insulin dose in adults with type 1 diabetes and obesity
Semaglutide Cuts Insulin Needs By Half In Type 1 Diabetes
A post hoc analysis of an RCT found that semaglutide 1 mg/week significantly reduced total daily insulin dose by 22.6% over 26 weeks in adul…
Semaglutide reduces insulin needs quickly in type 1 diabetes patients, offering a new hope for better blood sugar control and weight managem…
Systematic Review and Meta-Analysis: Bariatric Surgery Reduces Low Back Pain in Morbid Obesity
Metabolic surgery reduces back pain and improves spinal health in morbidly obese adults
This systematic review and meta-analysis of 390 morbidly obese adults found that metabolic and bariatric surgery significantly reduced low b…
Metabolic surgery significantly reduced back pain and improved quality of life for morbidly obese patients with low back pain, though spinal…
Wholegrain rye diets improve metabolic markers but not weight loss in overweight adults
Wholegrain rye lowers inflammation better than refined wheat for weight loss diets
This 12-week randomized trial compared hypocaloric diets with wholegrain rye versus refined wheat in 255 adults with overweight or obesity.
Switching to wholegrain rye while dieting may lower inflammation and improve gut bacteria even if weight loss is the same
Energy restriction with ultra-processed food restriction yields greater weight loss than generic energy restriction in obesity
Low-Processed Food Diet May Help People With Obesity Lose More Weight
This randomized clinical trial enrolled 148 individuals with obesity and compared energy restriction associated with ultra-processed food re…
A trial found that restricting ultra-processed foods alongside calorie limits helped people with obesity lose more weight and reduce ultra-p…
Oral Sodium Butyrate Reduces Weight in Overweight Adults Without Diabetes
Oral sodium butyrate helps overweight adults without diabetes lose weight
This 12-week proof-of-concept RCT in 46 overweight adults (23 with type 2 diabetes) found that oral sodium butyrate 1875 mg/day led to great…
A new trial shows oral sodium butyrate helps adults without diabetes lose more weight than a placebo over three months.
Exploratory analysis of RYGB and SG shows variable LDL cholesterol response in patients with obesity and high LDL cholesterol
Two bariatric surgeries lower cholesterol through completely different biological paths
This exploratory analysis of a randomized clinical trial (BASALTO) evaluated 30 patients with obesity and high LDL cholesterol undergoing Ro…
New research shows that two popular weight loss surgeries lower bad cholesterol in very different ways that could change how doctors pick a …
Extended sleep improved sleep metrics but did not change insulin sensitivity in a small trial
Extended sleep improves sleep duration but not insulin sensitivity in small trial
This randomized trial investigated whether extending sleep duration improves metabolic health in people with overweight or obesity and habit…
In a small trial, people with overweight or obesity who slept longer stayed in bed more and felt better, but insulin sensitivity did not imp…
Afternoon/Evening Exercise May Lower Blood Pressure More Than Morning Exercise: Meta-Analysis
Evening exercise lowers blood pressure and sugar better than morning workouts for people with diabetes or high weight
This systematic review and meta-analysis of 625 participants found that afternoon/evening exercise (PmEx) was associated with significantly …
For people with type 2 diabetes or high blood pressure, working out in the afternoon or evening lowers blood pressure and sugar more than mo…
Essential phospholipids reduced hepatic steatosis and improved HbA1c in patients with MASLD and type 2 diabetes over 6 months
Essential Phospholipids Reduce Liver Fat In Six Months
This randomised, placebo-controlled phase 4 trial enrolled 193 patients with metabolic dysfunction-associated steatotic liver disease and ty…
Essential phospholipids may lower liver fat and improve energy levels for people with fatty liver disease and diabetes within just six month…
Umbrella review identifies risk factors and protective factors for male infertility and semen quality
New study lists many things that hurt male fertility and health
This umbrella review of 43 studies synthesizes evidence on risk factors for male infertility and abnormal semen parameters.
A new review shows that obesity, smoking, and certain illnesses can hurt sperm, but healthy habits might fix the problem.