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Nephrology
Meta-analysis
Systematic review and meta-analysis of health coaching interventions in chronic kidney disease patients
Health coaching helps patients with kidney disease lose weight and lower blood pressure
This systematic review and meta-analysis evaluated health coaching interventions in patients with chronic kidney disease.
A review of health coaching shows patients with kidney disease lost weight and lowered blood pressure, though benefits were small and not al…
May 1, 2026
Nephrology
RCT
Amiloride and hydrochlorothiazide affect metabolites and ammonium excretion in CKD patients
Distal diuretics change kidney chemistry in people with chronic kidney disease
This randomized controlled trial in 26 individuals with chronic kidney disease found that distal diuretics decreased plasma glutamine and tr…
A small trial found that taking amiloride and hydrochlorothiazide lowered glutamine and changed how the body handles waste in people with ch…
May 1, 2026
Nephrology
Phase II
Kidney-directed SBRT shows modest renal function decline in inoperable patients
Small study shows kidney function drops after radiation for hard-to-treat tumors
This prospective phase 2 single-arm trial evaluated kidney-directed SBRT in 30 patients with primary or metastatic renal tumors who were med…
Radiation to treat kidney tumors may lower kidney function over two years, even when surgery is not an option.
May 1, 2026
Nephrology
RCT
Omega-3 fatty acids fail to reduce inflammation in hemodialysis patients
Short-term omega-3s did not lower inflammation in dialysis patients
This randomized controlled trial tested omega-3 fatty acids (3 g/day) for 2 months in patients with chronic kidney disease undergoing hemodi…
A trial found that taking omega-3 capsules for two months did not reduce inflammatory markers in patients with chronic kidney disease on hem…
May 1, 2026
Diabetes & Endocrinology
Meta-analysis
Meta-analysis shows associations between hypothyroidism and increased chronic kidney disease prevalence
Hypothyroidism Linked To Kidney Issues But Treatment Does Not Fix Them
This meta-analysis of 46 studies examines the relationship between hypothyroidism, including subclinical cases, and kidney outcomes.
Untreated low thyroid levels are strongly tied to worse kidney function in adults, but taking thyroid medicine does not seem to improve kidn…
Frontiers
May 1, 2026
Primary Care & Family Medicine
Cohort
Permanent night shift work associated with increased chronic kidney disease risk in UK Biobank participants
Permanent night shift work linked to kidney disease risk
This prospective cohort study of UK Biobank participants found an association between permanent night shift work and increased risk of incid…
Working permanent night shifts may increase your risk of developing chronic kidney disease, according to a large study of UK Biobank partici…
Frontiers
Apr 30, 2026
Allergy & Immunology
Sys. Review
Narrative review discusses renal risks in inflammatory bowel disease patients
Kidney risks for people with inflammatory bowel disease remain unclear and need more study
This narrative review examines renal complications in individuals with inflammatory bowel disease.
People with inflammatory bowel disease face kidney risks, but current evidence relies on animal studies and lacks human proof.
Frontiers
Apr 29, 2026
Cardiology
Sys. Review
Narrative review examines multimorbidity impact on sepsis morbidity and mortality outcomes
Sepsis Risk Skyrockets When You Have Multiple Chronic Conditions
This narrative review synthesizes evidence regarding sepsis in patients with multimorbidity including type 2 diabetes and heart failure.
Common chronic diseases like diabetes and heart failure create hidden traps that make sepsis much harder to fight and treat.
Frontiers
Apr 29, 2026
Nutrition & Obesity Medicine
Cohort
Higher TyG index linked to increased renal function progression risk in patients with CKD stages 3–4
High TyG Index Signals Faster Kidney Decline In Advanced Disease
This multicenter retrospective cohort study evaluated 53,607 patients with CKD stages 3–4.
A simple blood test number reveals who is at highest risk for rapid kidney failure among thousands of patients.
Frontiers
Apr 28, 2026
Nephrology
Meta-analysis
Individual-participant data meta-analysis shows blood-pressure lowering reduces cardiovascular risk in CKD and non-CKD populations
Blood pressure drugs protect kidneys and hearts across all stages
This individual-participant data meta-analysis pooled results from 46 randomised trials involving 285,124 participants to evaluate…
Lowering blood pressure protects the heart and kidneys across all stages of kidney disease, but the benefit is weaker in patients who also h…
Apr 27, 2026
Nephrology
Observational study links cutaneous microvascular function to chronic kidney disease severity
Skin blood flow changes may link to kidney disease
This observational study of 150 participants with chronic kidney disease (eGFR <90 mL/min/1.73 m2) investigated the relationship between cut…
New observations suggest that changes in skin blood flow patterns may be linked to how well your kidneys are functioning.
medRxiv
Apr 27, 2026
Neurology
RCT
Oral beraprost extends median survival in dogs with IRIS stage 2 chronic kidney disease compared to historical controls
Beraprost Adds Years to Dogs’ Lives with Early Kidney Disease
This prospective clinical study evaluated oral beraprost in dogs with naturally occurring IRIS stage 2 chronic kidney disease.
Dogs with early kidney disease who took a certain medication lived more than five times longer than those who didn’t — and vets are taking n…
Frontiers
Apr 25, 2026