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Pulmonology & Critical Care

133 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Systematic review links specific TCM constitutions to worse COPD outcomes in 2,168 patients
Pulmonology & Critical Care Meta-analysis
Systematic review links specific TCM constitutions to worse COPD outcomes in 2,168 patients TCM Constitution Types Linked to Worse COPD Outcomes
This systematic review and network meta-analysis examined Traditional Chinese Medicine (TCM) constitutions in 2,168 COPD patients. The autho…
A large analysis of 2,168 COPD patients found that specific Traditional Chinese Medicine constitution types were linked to lower lung functi…
Subcutaneous astegolimab reduced COPD exacerbations in phase 2b and 3 trials versus placebo
Pulmonology & Critical Care RCT
Subcutaneous astegolimab reduced COPD exacerbations in phase 2b and 3 trials versus placebo New drug cuts COPD flare-ups for some smokers in large trials
This randomized, double-blind, placebo-controlled phase 2b and 3 trial evaluated subcutaneous astegolimab in current or former smokers with …
A new medicine called astegolimab reduced severe breathing flare-ups for some people with COPD, though results varied by how often they took…
Case report of 3-year-old girl with bilateral Wilms tumor and TP53 mutation treated with VAD chemotherapy and surgery
Pulmonology & Critical Care Sys. Review
Case report of 3-year-old girl with bilateral Wilms tumor and TP53 mutation treated with VAD chemotherapy and surgery 3-year-old girl with TP53 mutation and bilateral Wilms tumor died after treatment
This case-based review describes a single 3-year-old girl with bilateral Wilms tumor and a TP53 mutation treated under the Chinese Children …
A single case report describes a 3-year-old girl with bilateral Wilms tumor and a TP53 mutation who died despite aggressive chemotherapy and…
Delayed arousal timing links to higher mortality in sleep apnea patients
Pulmonology & Critical Care Meta-analysis
Delayed arousal timing links to higher mortality in sleep apnea patients Timing of breathing pauses predicts death risk in obstructive sleep apnea
A meta-analysis found that each one-second delay in post-apnea arousal peak time was associated with increased all-cause and cardiovascular …
New analysis shows how late a breathing pause wakes you up predicts higher death risk for men with obstructive sleep apnea.
Case report suggests second primary glioblastoma in ALK-positive lung adenocarcinoma patient treated with ensartinib and lorlatinib
Pulmonology & Critical Care Sys. Review
Case report suggests second primary glioblastoma in ALK-positive lung adenocarcinoma patient treated with ensartinib and lorlatinib A single patient case warns doctors to check for second cancers when tumors act strangely
This case report describes a 63-year-old female with ALK-positive lung adenocarcinoma who received ensartinib, lorlatinib, and stereotactic …
A 63-year-old woman with lung cancer developed a new brain tumor that was not a metastasis. Doctors must carefully examine unusual tumor gro…
Systematic review and meta-analysis shows individualized EIT-guided PEEP reduces postoperative atelectasis in laparoscopic surgery patients
Pulmonology & Critical Care Meta-analysis
Systematic review and meta-analysis shows individualized EIT-guided PEEP reduces postoperative atelectasis in laparoscopic surgery patients Individualized EIT-guided PEEP reduces lung collapse after laparoscopic surgery
This systematic review and meta-analysis evaluated individualized EIT-guided PEEP versus fixed PEEP in 290 patients undergoing laparoscopic …
A meta-analysis shows individualized lung pressure settings guided by EIT reduce lung collapse and improve oxygenation after laparoscopic su…
FDA Approves Adempas (riociguat) for Chronic Thromboembolic and Pulmonary Arterial Hypertension
Pulmonology & Critical Care FDA Approval
FDA Approves Adempas (riociguat) for Chronic Thromboembolic and Pulmonary Arterial Hypertension FDA approves new pill Adempas for two types of high blood pressure in lungs
The FDA approved Adempas (riociguat) for adults with persistent/recurrent CTEPH after surgery or inoperable CTEPH, and for PAH (WHO Group 1)…
The FDA approved Adempas (riociguat) for two forms of pulmonary hypertension: chronic thromboembolic pulmonary hypertension (CTEPH) and pulm…
Post hoc reanalysis suggests stereotactic radiotherapy may improve local control in medically inoperable Stage I non-small cell lung cancer
Pulmonology & Critical Care RCT
Post hoc reanalysis suggests stereotactic radiotherapy may improve local control in medically inoperable Stage I non-small cell lung cancer New analysis gives hope for early lung cancer patients who cannot have surgery
This post hoc Bayesian reanalysis of the LUSTRE trial evaluated stereotactic radiotherapy versus conventional radiotherapy in medically inop…
A new statistical review suggests a focused radiation approach may better control early lung cancer for patients who cannot undergo surgery.
Meta-analysis finds immunotherapy improves survival in mesothelioma
Pulmonology & Critical Care Meta-analysis
Meta-analysis finds immunotherapy improves survival in mesothelioma Immunotherapy boosts survival time for mesothelioma patients across all treatment lines
This meta-analysis of 2549 patients with mesothelioma found that immunotherapy significantly improved overall survival (HR 0.78, p=0.0005). …
New research shows immunotherapy helps mesothelioma patients live longer, offering hope where few options existed before.
Systematic review and meta-analysis of repeat corticosteroids in PPROM shows increased maternal infection risk
Pulmonology & Critical Care Meta-analysis
Systematic review and meta-analysis of repeat corticosteroids in PPROM shows increased maternal infection risk Repeat steroid shots for PPROM may raise infection risk without helping babies
This systematic review and meta-analysis evaluated repeat courses of corticosteroids versus a single course in women with preterm premature …
A new review suggests giving two rounds of steroids to women with PPROM could hurt the mother without helping the baby
Real-world meta-analysis supports pembrolizumab for advanced NSCLC with high PD-L1
Pulmonology & Critical Care Meta-analysis
Real-world meta-analysis supports pembrolizumab for advanced NSCLC with high PD-L1 Real-world data confirms pembrolizumab offers long-term survival for advanced lung cancer patients
A systematic review and meta-analysis of real-world studies evaluated first-line pembrolizumab monotherapy for advanced NSCLC with high PD-L…
New data from thousands of patients shows pembrolizumab provides reliable long-term survival for advanced lung cancer without major safety s…
Meta-analysis shows biologic therapies reduce annual exacerbations in COPD patients with high eosinophils while maintaining safety profiles
Pulmonology & Critical Care Meta-analysis
Meta-analysis shows biologic therapies reduce annual exacerbations in COPD patients with high eosinophils while maintaining safety profiles New drugs cut COPD flare-ups for patients with high eosinophils
This living evidence synthesis evaluates dupilumab and mepolizumab in 7,359 COPD patients. Results indicate reduced annual exacerbation rate…
New biologic drugs lower the yearly number of COPD flare-ups for patients with high eosinophil counts while keeping side effects low

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