Respiratory microbiome composition in children offers new ideas for precision treatment of respiratory diseases and asthma
New ideas for treating children with asthma and respiratory infections
This narrative review examines the respiratory microbiome, metabolites, and colonization in children with respiratory infections, allergic a…
This review offers fresh directions for understanding how the respiratory microbiome affects children with asthma and allergic airway inflam…
Ultrasound may aid pediatric constipation diagnosis in various clinical settings
Ultrasound scans may help doctors diagnose constipation in children
This narrative review examines the role of transabdominal and perianal ultrasonography in pediatric gastroenterology clinics and institution…
Ultrasound scans could become a useful tool for doctors treating constipation in children, offering a new way to see inside without surgery.
Cluster RCT Protocol Tests Enhanced Early Childhood Development Program in Chinese Primary Care
New trial tests early childhood development program in China
This protocol describes a cluster randomized controlled trial testing an enhanced early childhood development (ECD) program in 1044 children…
A large trial in China is testing whether a program that improves health facilities and parenting support can boost early childhood developm…
High-dose quadrivalent influenza vaccine shows non-inferior immunogenicity in Chinese children aged 6 to 35 months
High-dose flu shots show greater protection for young children in China
This randomized, double-blind study in 3,000 Chinese children aged 6 to 35 months found an investigational high-dose quadrivalent influenza …
A new study in China shows high-dose flu vaccines work as well as or better than standard shots for toddlers, offering stronger protection a…
Systematic review and meta-analysis of levetiracetam efficacy in pediatric epilepsy patients
Levetiracetam shows seizure benefits over placebo in children with epilepsy
This systematic review and meta-analysis evaluated levetiracetam (LEV) in patients 16 years or younger with epilepsy. The analysis included …
A large analysis found levetiracetam improved seizure freedom and responder rates compared to placebo in children, though it did not consist…
Narrative review highlights distinct biological processes in pediatric suicidal behavior compared to adults
Biological markers of youth suicide differ from adults
This narrative review examines biological signatures of suicidal ideation, suicide attempts, and death by suicide in pediatric and adolescen…
A review suggests biological signs of suicidal thoughts in children and teens are distinct from adults, meaning adult data cannot explain yo…
Review of ruxolitinib for systemic juvenile arthritis with macrophage activation syndrome
Two children with severe arthritis found relief using a new drug approach
This narrative review synthesizes a retrospective case series and literature search on ruxolitinib for systemic juvenile idiopathic arthriti…
Two children with severe arthritis complications found relief using a new drug approach, offering hope for those who struggle with standard …
Case report describes bilateral simple excision in a 10-year-old child with cervical branchial remnants
Simple surgery removed rare neck growths in a 10-year-old child
This publication is a case report and review of the literature describing a 10-year-old child with bilateral cervical chondrocutaneous branc…
A 10-year-old child with rare neck growths had them removed with simple surgery, showing no safety concerns in this single case report.
Achievement emotions and working memory correlate with second language learning in primary school students
Emotions and relationships matter for young students learning a second language
This systematic review and meta-analysis evaluated 19 primary studies involving 5,340 participants to examine factors influencing second lan…
A large review shows how feelings like anxiety and closeness to teachers directly impact how well primary school students learn a second lan…
GSK investigational MMRV vaccine shows comparable immunogenicity to licensed MMRV in healthy children
GSK MMRV vaccine shows comparable safety and immune response to licensed MMRV in young children
This randomized, multi-country phase II trial in 801 healthy children aged 4-6 years found that one dose of a GSK investigational MMRV vacci…
A Phase II trial in healthy children found the investigational GSK MMRV vaccine produced immune responses and safety similar to the licensed…
Case report confirms X-linked Alport syndrome diagnosis in a young girl with family history
Early testing confirms X-linked Alport syndrome in a toddler
This case report describes a 4-year-2-month-old girl with X-linked Alport syndrome who underwent renal biopsy and genetic testing. The diagn…
A young girl with a family history of kidney disease received a quick diagnosis through biopsy and genetic tests.
Systematic review of orthognathic surgery outcomes in 6,482 patients with dentofacial deformities
Orthognathic surgery improves jaw alignment and quality of life for thousands of patients
This systematic review and meta-analysis evaluated clinical outcomes for orthognathic surgery in 6,482 patients with dentofacial deformities…
A large review of over 6,000 patients shows orthognathic surgery improves jaw alignment and quality of life, with most nerve issues resolvin…
All Pediatrics Articles
- Respiratory microbiome composition in children offers new ideas for precision treatment of respiratory diseases and asthma
- Ultrasound may aid pediatric constipation diagnosis in various clinical settings
- Case report describes bilateral simple excision in a 10-year-old child with cervical branchial remnants
- High-dose quadrivalent influenza vaccine shows non-inferior immunogenicity in Chinese children aged 6 to 35 months
- Cluster RCT Protocol Tests Enhanced Early Childhood Development Program in Chinese Primary Care
- Narrative review highlights distinct biological processes in pediatric suicidal behavior compared to adults
- Review of ruxolitinib for systemic juvenile arthritis with macrophage activation syndrome
- Systematic review and meta-analysis of levetiracetam efficacy in pediatric epilepsy patients
- Case report confirms X-linked Alport syndrome diagnosis in a young girl with family history
- Systematic review of orthognathic surgery outcomes in 6,482 patients with dentofacial deformities
- Achievement emotions and working memory correlate with second language learning in primary school students
- GSK investigational MMRV vaccine shows comparable immunogenicity to licensed MMRV in healthy children
- Guideline secondary analysis shows non-significant trend for higher enteral nutrition use in pediatric Crohn's disease registry groups
- Narrative review of Digital First Primary Care model in NHS England patients
- Meta-analysis shows early kangaroo care reduces mortality in very preterm infants compared to conventional care
- Systematic review and meta-analysis of liposomal iron versus conventional iron in pediatric iron deficiency anemia
- Narrative review discusses paradoxical inflammatory reactions in pediatric patients receiving biologic therapy
- Systematic review and meta-analysis links pRBC transfusion to NEC deterioration in neonates
- Systematic review and meta-analysis links pediatric cerebral AVMs with congenital heart defects and outlines prognostic factors
- Systematic review of educational programs and system improvements for organ donation barriers
- Systematic review maps 50 most-cited articles on pediatric respiratory infections
- Systematic review and meta-analysis links prenatal NSAIDs to higher kidney disease risk in children
- Planned early birth reduces maternal morbidity and stillbirth risk in late preterm hypertensive disorders of pregnancy
- Structured parenting programme improves emotion regulation strategies in Swedish parents of toddlers
- Vital pulp therapy shows higher success odds than root canal in immature teeth
- Systematic review and meta-analysis of laser fluorescence devices for detecting dental caries in children
- Childhood Immunization Coverage in Somalia Remains Critically Low
- Review of a case of Down syndrome T-ALL with complex karyotype and treatment response
- Meta-analysis shows oral zinc sulfate significantly lowers bilirubin levels in infants with neonatal hyperbilirubinemia across multiple time points
- Meta-analysis compares Herbst and Twin Block appliances for Class II malocclusion in growing patients
- Meta-analysis shows infants prefer prosocial puppets but findings lack generalizability outside North America
- Systematic review links shorter newborn transfer times to better survival in LMICs and HICs
- Meta-analysis finds coaching improves teacher practice and child outcomes in early childhood settings
- Systematic review and meta-analysis compares Rome III and Rome IV criteria for functional abdominal pain disorder prevalence
- FDA Approves Dextrose 5% Injection for Hydration and Calorie Source
- Azithromycin at discharge does not reduce pneumococcal carriage in Kenyan children
- Narrative review on pediatric perianal abscess management and fistula risk
- Meta-analysis finds antibiotics alone comparable to drainage for pediatric post-appendectomy abscess
- Narrative review on pediatric otitis media risk factors and biomarkers
- Meta-analysis provides normative pediatric sleep data across age groups
- Narrative review examines neuropsychiatric manifestations of celiac disease in pediatric and adult populations
- Review synthesizes IQSEC2 variant features in developmental encephalopathy and Rett-like syndrome cases
- Systematic review and meta-analysis on postoperative dysglycemia prevalence in pediatric cardiac surgery
- Pediatric Gut Microbiome Links to Metabolic Dysfunction-Associated Steatotic Liver Disease and Type 2 Diabetes
- Systematic Review and Meta-Analysis Finds IL-27 Superior to CRP for Neonatal Sepsis Diagnosis
- Narrative review finds insufficient evidence for CFTR modulator monotherapy in cystic fibrosis with F508del homozygosity
- Systematic review and meta-analysis of laparoscopic versus open repair for pediatric incarcerated inguinal hernia
- Meta-analysis finds Xingpi Yanger Granule plus conventional therapy reduces nocturnal enuresis frequency in children
- Systematic review and meta-analysis shows higher wound dehiscence risk with single-stage repair for anorectal malformations in neonates and infants
- Meta-analysis on language sample analysis for developmental language disorder in bilingual children
- Ondansetron home use for pediatric acute gastroenteritis vomiting after ED discharge
- Systematic review and meta-analysis links higher maternal BMI to increased early-onset Group B Streptococcus disease risk
- Systematic review and meta-analysis shows Twin-Block appliance reduces AHI in pediatric obstructive sleep apnea
- Meta-synthesis of nurses' perspectives on pediatric pain management reveals key themes
- Meta-analysis of nonpharmacological interventions for young autistic children finds limited moderation by cognitive or language scores
- Protocol for a future systematic review on pediatric limb arteriovenous malformations
- Systematic review and meta-analysis compares single-port versus two-port laparoscopic pediatric inguinal hernia repair
- Clinical practice guideline for pediatric flexible flatfoot: conservative and surgical options
- Meta-analysis finds no clear difference between amoxicillin and other antibiotics for community-acquired pneumonia
- Meta-analysis finds high mortality and morbidity for neonates on mechanical ventilation in low-resource settings
- Systematic review and meta-analysis compares piperacillin-tazobactam and cefepime in pediatric febrile neutropenia
- Systematic review suggests interdental brushes may reduce plaque and inflammation in orthodontic patients compared with other methods
- Review of pediatric fundoscopic evaluation for increased intracranial pressure
- Scoping review of fetal lymphangioma management in a case report series
- Meta-analysis compares total vs partial fundoplication for pediatric GERD
- FDA Approves Children's Advil (ibuprofen) for Fever and Minor Aches in Children
- FDA Approves Children's Advil (ibuprofen) for Fever and Minor Aches in Children
- Systematic review and meta-analysis on BCG lymphadenitis incidence in healthy children
- FDA Approves Ngenla (somatrogon-ghla) for Pediatric Growth Hormone Deficiency
- Literature review enhances awareness and management strategies for plastic bronchitis in pediatric populations
- Exercise improves social functioning in children with ADHD, optimal dose identified
- Systematic review and meta-analysis of sensory integration therapy for children shows mixed motor and functional outcomes
- Clinical decision support tool improves pediatric hypertension recognition in rural clinics
- Meta-analysis finds Laryngeal EMG moderately predicts vocal cord paralysis recovery in children
- Systematic review and meta-analysis finds ventriculosubgaleal shunt safe in premature neonates with posthemorrhagic hydrocephalus
- Systematic review and meta-analysis of AI for infant hip ultrasound accuracy
- Systematic review and meta-analysis on motor delay prevalence in children with craniosynostosis
- Meta-analysis finds 24% incidence of cognitive dysfunction after pediatric liver transplant
- UK trial reports 4-year event-free survival of 63% and overall survival of 68% in relapsed Wilms tumour patients
- Audiobooks with scaffolding improve vocabulary in elementary students
- Therapeutic Touch Reduces Crying and Improves Sleep in Infants With Colic
- Mycophenolate mofetil non-inferior to prednisone for first-episode nephrotic syndrome in children
- AquOTic water competency intervention improves outcomes in children with autism
- Play-based cognitive flexibility training boosts creativity in third graders
- Adenotonsillectomy with turbinate ablation shows no added benefit for pediatric SDB
- Operating microscope use increased operative time in cleft palate repair for infants under two years
- Enhanced face-washing intervention increases soap use in trachoma-endemic Ethiopia
- Infant formula with dairy lipids showed no difference in fat mass compared to control formula or exclusive breastfeeding
- Nicotinamide Riboside Plus Exercise Improves Fitness in Friedreich's Ataxia
- Combined low-level laser and ultrasound therapy showed possible efficacy and safety for growing pains in children over 30 days
- Systematic review and meta-analysis of canonical babbling ratio trajectories in infants aged 5 to 24 months across 42 studies
- Meta-analysis shows moderate positive learning effects from physically embodied educational robots in classrooms
- Systematic review meta-analysis shows higher complication rates in young children undergoing tonsillectomy
- Systematic review and meta-analysis supports adalimumab plus methotrexate for JIA-associated uveitis
- Meta-analysis shows Mycoplasma pneumoniae prevalence in children varied before, during, and after COVID-19
- Meta-analysis shows integrated nursing interventions improve outcomes in paediatric severe pneumonia
- MiniDock MTB Test Shows High Sensitivity and Specificity for Tuberculosis Detection
- Meta-analysis shows clear aligners produce less skeletal expansion than conventional appliances in growing patients
- Congenital urinary tract dilation resolves spontaneously in 96.2% of children over 3 to 44 months follow-up
- Containment surgery and radiographic outcomes in children with Waldenström stage III LCPD
- Disease progression and death in a 10 year old male with lower esophageal squamous cell carcinoma
- Azithromycin to doxycycline switching in children with Mycoplasma pneumoniae pneumonia resistance gene positivity
- Routine lab indicators help differentiate typical from incomplete Kawasaki disease and predict coronary lesions
- Narrative review discusses telemedicine potential and barriers for new immigrant children in the US
- Pregnant women unvaccinated against pertussis had infants with higher anti-PT IgG levels at six months
- Valganciclovir dosing in congenital cytomegalovirus infection shows extensive drug accumulation in dried blood spots
- High-dose rifampicin pharmacokinetics differ across sites in tuberculosis infection randomized trial
- Six H5N1 vaccine formulations showed immunogenicity and acceptable safety in 420 healthy children aged 6 months to 9 years
- Vitamin A Supplementation at Birth Alters Vaccine Immune Responses Without Improving Antibody Levels in Infants
- Autologous hematopoietic stem cell transplantation improves disease-free survival in pediatric extraocular retinoblastoma patients
- Weekend births linked to longer antibiotic exposure in very low birth weight infants with suspected sepsis
- Supervised exercise in pediatric oncology: low rate of adverse events over 3 years
- Systematic review and meta-analysis identifies factors associated with hearing recovery in pediatric sudden hearing loss
- Case report and review of literature on Aggregatibacter actinomycetemcomitans lung infection in a child
- Network meta-analysis of ketamine regimens for pediatric ED procedural sedation safety and efficacy
- FDA Approves Crysvita (burosumab) for X-Linked Hypophosphatemia and Tumor-Induced Osteomalacia
- Fetal paracetamol exposure linked to reduced ovarian and uterine volume in girls
- Eltrombopag plus immunosuppression for severe aplastic anemia shows clonal evolution patterns
- Meta-analysis compares robot-assisted versus laparoscopic surgery for pediatric choledochal cyst
- Leuprolide acetate associated with final adult height exceeding mid-parental height in girls with central precocious puberty
- Long peripheral catheters reduce infusion failure compared to short catheters in late preterm and term neonates
- Woodward procedure associated with improved outcomes in pediatric Sprengel deformity patients
- GI multiplex PCR testing in children with acute gastroenteritis showed high positivity and guided antibiotic stewardship
- Case report and literature review on mosaic DICER1 mutations and disease stability in a 6-month-old boy
- Systematic review and meta-analysis compares ESIN versus plating for pediatric femoral shaft fractures
- Meta-analysis of ketamine versus other analgosedatives in critically ill children receiving invasive mechanical ventilation
- L9LS monoclonal antibody reduces malaria infection in children in western Kenya
- Burosumab improves phosphate levels in 12 children and adults with fibrous dysplasia over 48 weeks
- Review of RANBP2 variant carriers shows exaggerated TNF- responses and distinct immunologic signature in acute necrotizing encephalopathy
- PGx testing with education improved understanding and perceived utility compared to test results alone in a randomized trial
- Decision-support model predicts failed closed reduction in pediatric supracondylar humerus fractures
- Radiomics features on MRI discriminate sellar LCH from tumor marker-negative GCTs with an AUC of 0.81
- Narrative review on pediatric RSV co-infections and post-pandemic rebound
- Narrative review examines high-risk factors and major nursing interventions for bronchopulmonary dysplasia in premature infants
- Systematic review and meta-analysis of vosoritide in children with achondroplasia shows growth gains and injection site reactions
- Early enteral feeding during hypothermia for neonatal HIE shows no GI adverse event link
- Retrospective review of neonatal bacterial meningitis outcomes and pathogen associations in 531 term neonates
- Retrospective study compares antibiotic regimens for H. pylori eradication in children
- Ultrasound guidance and radial artery insertion improve first-attempt success in critically ill children
- Multi-BOUNTI deep learning pipeline enables rapid automated multi-lobe segmentation of fetal and neonatal T2w brain MRI
- Telemedicine family care guidance improves neurodevelopment in premature infants
- Repeated red light therapy reduces axial length elongation in premyopic children over 24 months
- Five-Year Book Distribution Program Increases Reading Achievement in High-Poverty Elementary Schools
- Review of skull-base osteomyelitis management highlights individualized strategies and monitoring gaps
- Combined Therapy for Febrile Ulceronecrotic Mucha-Habermann Disease in Young Children: Case Report and Review
- Systematic review and meta-analysis shows reduced lung function in children with post-tuberculosis treatment compared to healthy controls
- Systematic review and meta-analysis of atropine for myopia control in children
- Dataset describes continuous monitoring in premature VLBW infants across four US NICUs
- Admission blood glucose levels associated with NRDS severity in neonates
- In a single-center retrospective cohort of 107 pediatric patients, food was the most common anaphylaxis trigger at 62.61%
- Retrospective study links SMA type 1 to higher hip instability prevalence in children
- Small-Group Reading Intervention Shows Differential Gains in ADHD, BIF, Dyslexia
- Macrolide-resistant Mycoplasma pneumoniae prevalence at 94% in pediatric CAP cohort
- Laparoscopic vs open inguinal hernia repair in children: cohort study reports differences in outcomes
- Systematic review of mobile health just-in-time adaptive interventions for youth mental health and substance use
- Meta-analysis of maternal Chikungunya infection and pregnancy outcomes
- Narrative review on parental involvement in neonatal decision-making
- Washed microbiota transplantation in a malnourished child with resistant Klebsiella and Candida infections
- Esketamine vs fentanyl for pediatric tonsillectomy pain shows comparable FLACC scores
- Prophylactic azithromycin during labor increases S. aureus resistance in mothers and infants
- Network meta-analysis finds medium-dose vitamin A superior to high-dose for pediatric pneumonia
- Rural Trauma Team Development Course Shortens Prehospital Time and Lowers Mortality in Uganda
- Vosoritide daily injections in prepubertal hypochondroplasia patients over 12 months
- Digital and strip-based salivary pH measurements assessed for caries risk in 66 school-aged children
- Retrospective analysis of 326 infants with infantile cholestasis reveals etiological spectrum
- Bismuth-containing quadruple therapy associated with higher H. pylori eradication rates compared to triple therapy in children
- Emergency call training improves number recall in German elementary school pupils aged 7 to 9 years
- Protocol for Global Integration Method in children with ASD aged 6 to 12 years
- De-implementation of low-value bronchiolitis practices showed sustained adherence two years post-trial in a cluster RCT follow-up
- Systematic Review and Network Meta-Analysis Compares Enteral Nutrition and Medications in Pediatric Crohn's Disease
- Meta-analysis of combination ambroxol and clenbuterol therapy for pediatric wheezing disorders shows improved outcomes
- Meta-analysis indicates increased BMI SD scores with long-acting growth hormone versus daily rhGH in children
- Review of home-based bibliotherapy for fear of the dark in children aged 4 to 8 years
- Non-surgical casting versus surgical reduction for severely displaced distal radial fractures in children aged 4-10 years
- Retrospective case series evaluates omalizumab efficacy in Chinese pediatric chronic spontaneous urticaria patients
- Zinc-L-carnosine supplement versus thickened formula for persistent infant regurgitation in randomized trial
- Narrative review discusses systemic-to-pulmonary shunts for complex congenital heart defects in pediatric populations
- Case report of two neonates with esophageal atresia and phrenic nerve palsy managed with stepwise respiratory and surgical strategies
- Qualitative review of caregiver experiences for children with congenital craniofacial anomalies in Colombia
- Parechovirus A detection linked to pharyngitis and tonsillitis in children across hospital and day-care settings
- CC-FocusNet deep learning framework improves diagnostic accuracy for corpus callosum abnormalities in fetuses
- Systematic review and meta-analysis on adjunctive corticosteroids for orbital cellulitis in children
- Extended Caffeine Therapy Reduces Intermittent Hypoxia Burden in Very Preterm Infants in Randomized Trial
- Non-pharmacological de-escalation techniques used in Australian EDs for children with acute severe behavioural disturbance
- Backup ventilation timing after apnoea in extremely preterm infants on nCPAP
- Continuous glucose monitoring in very preterm infants shows low ketones and higher lactate in first week
- Closed-loop oxygen control shortens ventilation and oxygen duration in preterm infants in RCT
- Full milk feeds from birth show no difference in hospital stay but lower costs for preterm infants
- Systematic review and meta-analysis finds no clear benefit or harm for umbilical cord strategies on IVH risk in preterm neonates
- Point-of-care ultrasound diagnostic accuracy for pediatric appendicitis in emergency departments
- Review examines multi-omics approaches to enhance diagnostic precision and treatment decisions in pediatric neuroblastoma
- Quarterly triptorelin showed comparable hormonal suppression to monthly dosing in Chinese girls with central precocious puberty
- Review of single-stage surgery for orbital and parasellar infantile hemangioma in a 55-day-old infant
- Retrospective Cohort Examines Brain Development in Very Low Birth Weight Infants
- Anesthesia and Surgical Factors Linked to Postoperative Low Thyroid Hormone in Children
- Factors associated with time to discharge among preterm neonates in a Ugandan NICU retrospective cohort study
- Paracetamol or ibuprofen treatment outcomes in preterm infants with patent ductus arteriosus: a retrospective cohort analysis
- Guideline review addresses triplane fractures in adolescents without consensus on treatment frameworks
- Systematic review examines neonatal hyperbilirubinemia management strategies in high-altitude regions
- Markerless motion capture shows moderate agreement with marker-based systems in pediatric gait analysis