Short-term liraglutide modulates proteins in obesity, showing weight-independent effects and myostatin suppression
Could a weight-loss drug work by changing your body's proteins?
A 5-week randomized trial in 20 adults with obesity found liraglutide 3 mg daily modulated 124 proteins, with 85% of effects persisting afte…
A weight-loss drug changed 124 blood proteins in a small study, with 85% of shifts not tied to weight loss, hinting at deeper body-wide effe…
Nutrition and health canteen intervention linked to weight reduction in middle-aged adults
Nutrition-focused workplace canteen program linked to weight loss in middle-aged adults
A single-group before–after study of 97 middle-aged adults in China found a multifaceted nutrition and health canteen intervention was assoc…
A 12-week workplace canteen program in China helped middle-aged adults lose weight by offering diverse foods and reducing salt, sugar, and o…
Horseshoe-like plantar hyperkeratosis associated with prediabetes in overweight adults
Could a specific foot skin change be a visible clue for prediabetes?
A cross-sectional cohort study of 191 adults with overweight or obesity found horseshoe-like plantar hyperkeratosis (HSLPH) was more frequen…
A horseshoe-shaped patch of thickened skin on the foot is a strong visual clue for prediabetes in adults with overweight or obesity.
Post hoc analysis links WHtR threshold to remission in obesity management with tirzepatide vs semaglutide
Could hitting specific weight targets help people feel better?
A post hoc analysis of the SURMOUNT-5 trial in participants with obesity found that 23.1%-33.9% on tirzepatide and 14.2%-20.7% on semaglutid…
People on tirzepatide who hit a waist-to-height ratio under 0.53 had more than double the odds of reaching remission compared to those who d…
Walking program improves liver enzymes and BMI in children with PKU and NAFLD
Walking program shows improvement in liver health markers for children with PKU and fatty liver
An 8-week RCT in 40 overweight/obese children with PKU and NAFLD found that a free walking program significantly improved BMI, ALT, GGT, ALP…
An 8-week walking program improved liver health markers and BMI in children with PKU and fatty liver disease.
High BMI polygenic risk score linked to faster weight regain in postmenopausal European American women
Genetic risk score linked to faster weight regain in some postmenopausal women after weight loss
This RCT analysis of 9,897 postmenopausal women found that European Americans with ≥95th percentile BMI polygenic risk score regained nearly…
Women with high genetic risk for weight gain regained nearly twice as much weight per year after losing weight, but only if they were Europe…
NHANES data show rising obesity and severe obesity prevalence in US youth aged 2-19 years
Obesity and severe obesity rates increased among U.S. children and teens over two decades
An observational analysis of NHANES survey data found the prevalence of obesity among US youth aged 2-19 years increased from 13.9% to 19.3%…
U.S. children and teens saw obesity rates climb from 13.9% to 19.3% and severe obesity jump from 3.6% to 6.1% between 1999 and 2018.
Hospitalized pregnant women with COVID-19 had higher prepregnancy obesity and gestational diabetes prevalences
Study finds higher obesity and diabetes rates in pregnant women hospitalized for COVID-19
An observational report from eight U.S. health centers found hospitalized pregnant women with COVID-19-related illness had higher prevalence…
Pregnant women hospitalized for COVID-19 illness had higher rates of obesity and gestational diabetes than those admitted for pregnancy care…
US study examines obesity prevalence among children and adolescents aged 2-19 years
Study examines obesity and severe obesity rates in U.S. children and teens
An observational study assessed the prevalence of obesity and severe obesity among persons aged 2-19 years in the United States.
A new report shows how common obesity and severe obesity are among U.S. children and teens aged 2 to 19 years.
Scuba-diving and mindfulness program reduces emotional eating in adults with obesity in small trial
Scuba diving and mindfulness program reduced emotional eating in small obesity study
A small, unblinded RCT of 63 adults with obesity found that adding a 2-month therapeutic scuba-diving and mindfulness program to standard ca…
A two-month scuba diving and mindfulness program significantly reduced emotional eating and stress in adults with obesity compared to standa…
FDA Approves FOUNDAYO (orforglipron) for chronic weight management in adults with obesity or overweight with comorbidities
The FDA has approved a new daily pill called FOUNDAYO to help adults manage their weight
The FDA has approved FOUNDAYO (orforglipron), an oral GLP-1 receptor agonist, for chronic weight management in adults with obesity or overwe…
FDA approves new daily pill FOUNDAYO for adults to manage weight alongside diet and exercise.
Lorcaserin reduces weight and fat mass, alters lipidomics in 48 adults with obesity over 6 months
Small study finds lorcaserin reduces weight and fat in adults with obesity
A 6-month randomized controlled trial in 48 adults with obesity found lorcaserin (10 mg twice daily) reduced total body weight, total body f…
Adults with obesity taking lorcaserin lost more total weight and abdominal fat than those taking a placebo pill over six months.