D-VCd improves hematologic CR rate to 59.5% compared to 19.2% in AL amyloidosis
Trial shows adding daratumumab improves outcomes for AL amyloidosis
Aug 28, 2026
This Phase 3 randomized controlled trial of 388 patients with newly diagnosed AL amyloidosis found that adding subcutaneous daratumumab to VCd significantly imp…
Adding daratumumab to a standard drug combination helps patients with AL amyloidosis achieve faster and deeper responses in blood and organ health.
Rezpegaldesleukin Demonstrates Significant Efficacy in Moderate to Severe Atopic Dermatitis Patients
New treatment shows promise for moderate to severe atopic dermatitis
Aug 28, 2026
Rezpegaldesleukin showed significant reductions in EASI scores for adults with atopic dermatitis, demonstrating high efficacy and a manageable safety profile.
A new medication shows significant improvement in skin symptoms for adults with moderate to severe atopic dermatitis compared to a placebo.
Obinutuzumab improves SRI-4 response by 23.1 percentage points in active systemic lupus erythematosus
Trial shows obinutuzumab improves outcomes for systemic lupus erythematosus
Aug 28, 2026
This Phase 3 randomized controlled trial of 303 adults with active systemic lupus erythematosus found obinutuzumab significantly superior to placebo for SRI-4 r…
A new clinical trial shows that obinutuzumab significantly improved response rates for adults with active systemic lupus erythematosus compared to a placebo.
Oral microbiome dysbiosis is observed in children and adolescents with chronic kidney disease
Oral health changes linked to chronic kidney disease in children
Aug 28, 2026
This systematic review of 7 studies examines oral microbiome alterations in pediatric patients with CKD, dialysis, or kidney transplantation. Findings indicate …
New research explores how the bacteria in a child's mouth change when they have chronic kidney disease.
Vestibular rehabilitation improves balance, walking speed, and reduces dizziness in patients with multiple sclerosis
Vestibular rehabilitation improves balance and walking for people with MS
Aug 28, 2026
This meta-analysis of 454 patients with multiple sclerosis found that vestibular rehabilitation significantly improved balance, walking speed, and reduced dizzi…
Vestibular rehabilitation can improve balance, walking speed, and reduce dizziness and fatigue for people living with multiple sclerosis.
HER2, PD-L1, MSI/MMR, and CLDN18.2 biomarkers may guide treatment selection in gastric cancer conversion therapy
Biomarkers help doctors choose better treatments for gastric cancer
Aug 28, 2026
This narrative review explores the clinical utility of HER2, PD-L1, MSI/MMR, and CLDN18.2 biomarkers in patients with gastric cancer undergoing conversion thera…
New markers like HER2 and CLDN18.2 help doctors identify which gastric cancer patients might respond best to specific therapies before surgery.
Protein-energy wasting prevalence reaches 47.0% among patients with chronic kidney disease in Africa
Nearly half of African kidney disease patients suffer from malnutrition
Aug 28, 2026
This meta-analysis of 25 studies involving 2822 participants identifies a 47.0% pooled prevalence of protein-energy wasting (PEW) in African patients with chron…
Nearly half of patients with chronic kidney disease in Africa suffer from protein-energy wasting, a serious form of malnutrition.
Desipramine shows large effect in adolescent MDD while other antidepressants show no significant difference
Analysis shows only one antidepressant outperformed placebo for teen depression
Aug 28, 2026
This systematic review and network meta-analysis evaluated five antidepressants for adolescent MDD. While desipramine showed a large effect size (SMD -1.80) com…
New data reveals that while most common antidepressants showed no significant difference from a placebo for teens with depression.
MULTIPL biomarker identifies patients with significantly longer overall survival on gemcitabine plus nab-paclitaxel
Trial Shows Biomarker Helps Identify Best Treatment for Pancreatic Cancer
Aug 28, 2026
This randomized Phase II trial and training cohort evaluated the MULTIPL biomarker in 160 and 268 patients with metastatic pancreatic ductal adenocarcinoma. The…
A new biomarker tool may help doctors choose the most effective chemotherapy for patients with metastatic pancreatic cancer.
Lithium-associated nephrogenic diabetes insipidus may cause severe postoperative hypernatremia and polyuria
Lithium use may cause kidney issues after surgery in patients
Aug 28, 2026
This case report describes a patient with schizophrenia and type 2 diabetes who developed severe hypernatremia and polyuria following a pancreatectomy while on …
A man with schizophrenia and diabetes faced severe complications after surgery, highlighting how lithium can affect kidney function and fluid balance.
Dairy proteins favor acute metabolic markers while pea protein may favor gut microbiota profiles
Dairy and pea protein offer different benefits for older adults
Aug 28, 2026
This narrative review synthesizes preclinical and clinical data comparing pea and dairy proteins in older adults. Dairy proteins favor acute postprandial metric…
Choosing between pea and dairy protein depends on your goals, as each offers unique benefits for gut health, muscle growth, and brain function.
Surgical resolution of insulinoma may not fully reverse chronic hypoglycemia-induced peripheral neuropathy
Surgery Can Help Reverse Nerve Damage From Low Blood Sugar
Aug 28, 2026
This case report and literature review describes a patient with a solitary pancreatic insulinoma and associated hypoglycemic polyneuropathy. While surgical inte…
A case study shows that surgery to remove a pancreatic tumor can resolve low blood sugar and improve some nerve damage.