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Pulmonology & Critical Care

133 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Meta-analysis finds balance training improves balance in COPD patients receiving pulmonary rehabilitation
Pulmonology & Critical Care Meta-analysis
Meta-analysis finds balance training improves balance in COPD patients receiving pulmonary rehabilitation Adding Balance Training to COPD Rehab Changes Lives
This meta-analysis of seven randomized trials in COPD patients aged 50 years or older found that adding balance training to pulmonary rehabi…
A simple addition to standard lung rehab, balance training, helps COPD patients stand steadier, feel more confident, and live better, a new …
FDA Approves Breztri Aerosphere (budesonide/glycopyrrolate/formoterol) for COPD Maintenance
Pulmonology & Critical Care FDA Approval
FDA Approves Breztri Aerosphere (budesonide/glycopyrrolate/formoterol) for COPD Maintenance FDA approves new triple-combination inhaler Breztri Aerosphere for COPD.
The FDA approved Breztri Aerosphere (budesonide/glycopyrrolate/formoterol fumarate) for maintenance treatment of COPD. It is a triple-combin…
The FDA approved Breztri Aerosphere, a triple-combination inhaler, for the long-term treatment of chronic obstructive pulmonary disease (COP…
Lung Ultrasound Shows Good Diagnostic Accuracy for ARDS in Meta-Analysis of 5888 Patients
Pulmonology & Critical Care Meta-analysis
Lung Ultrasound Shows Good Diagnostic Accuracy for ARDS in Meta-Analysis of 5888 Patients Lung ultrasound shows high accuracy for detecting severe breathing trouble in ICU patients
This systematic review and meta-analysis of 5888 patients found that lung ultrasound (LUS) has good diagnostic accuracy for acute respirator…
A large review of 5,888 patients found lung ultrasound is a highly accurate, safe way to check for severe lung injury without using radiatio…
Pembrolizumab improves overall survival versus chemotherapy in Chinese patients with advanced NSCLC and PD-L1 expression
Pulmonology & Critical Care RCT
Pembrolizumab improves overall survival versus chemotherapy in Chinese patients with advanced NSCLC and PD-L1 expression Five-year follow-up shows pembrolizumab extends life for Chinese lung cancer patients with high PD-L1
This Phase 3 trial evaluated pembrolizumab monotherapy against chemotherapy in Chinese patients with previously untreated locally advanced o…
A five-year look at a Chinese lung cancer trial shows pembrolizumab improved survival compared to chemotherapy for patients with high PD-L1 …
Toripalimab plus anlotinib maintenance shows promise in ES-SCLC after first-line chemo
Pulmonology & Critical Care Phase II
Toripalimab plus anlotinib maintenance shows promise in ES-SCLC after first-line chemo New combo therapy extends life for advanced small cell lung cancer patients
This multi-center, single-arm phase II trial evaluated maintenance toripalimab plus anlotinib in 20 patients with extensive-stage small cell…
A new drug pair extends life for advanced lung cancer patients by changing how their immune system fights back
Combination therapy shows promising progression-free survival in advanced non-small cell lung cancer patients with high PD-L1 expression
Pulmonology & Critical Care RCT
Combination therapy shows promising progression-free survival in advanced non-small cell lung cancer patients with high PD-L1 expression Early trial shows two-drug combo may help advanced lung cancer patients
This randomized phase 2 trial evaluated domvanalimab plus zimberelimab compared to zimberelimab alone or chemotherapy in patients with advan…
A Phase 2 trial suggests a two-drug combination might improve outcomes for some patients with advanced lung cancer compared to standard chem…
Evidence-based review of transducer selection for lung ultrasound in dogs and cats with pulmonary pathology
Pulmonology & Critical Care Sys. Review
Evidence-based review of transducer selection for lung ultrasound in dogs and cats with pulmonary pathology Choosing the right ultrasound probe can improve lung diagnoses for dogs and cats
This evidence-based review examines transducer selection for lung ultrasound in dogs and cats with pulmonary pathology.
Veterinary lung ultrasound accuracy depends on probe choice. This review highlights how transducer selection affects diagnosis in emergency …
Meta-analysis shows platinum-etoposide plus PD-1/PD-L1 inhibitor improves survival in extensive-stage small-cell lung cancer
Pulmonology & Critical Care Meta-analysis
Meta-analysis shows platinum-etoposide plus PD-1/PD-L1 inhibitor improves survival in extensive-stage small-cell lung cancer Adding PD-1 or PD-L1 inhibitors improves survival for extensive-stage small-cell lung cancer
This meta-analysis of phase III trials evaluated platinum-etoposide combined with a PD-1 or PD-L1 inhibitor versus platinum-etoposide alone …
Adding a PD-1 or PD-L1 inhibitor to standard chemotherapy improves survival for extensive-stage small-cell lung cancer without increasing se…
Systematic review and meta-analysis shows immune checkpoint inhibitors improve survival in first-line ES-SCLC but not as single agents in second-line
Pulmonology & Critical Care Meta-analysis
Systematic review and meta-analysis shows immune checkpoint inhibitors improve survival in first-line ES-SCLC but not as single agents in second-line Immune drugs boost survival in small-cell lung cancer
This systematic review and meta-analysis evaluates immune checkpoint inhibitors combined with chemotherapy versus chemotherapy alone for ext…
Adding immune checkpoint inhibitors to chemotherapy helps patients with extensive-stage small-cell lung cancer live longer.
Network meta-analysis of anti-PD-1/PD-L1 regimens in advanced non-squamous NSCLC without EGFR or ALK alterations
Pulmonology & Critical Care Meta-analysis
Network meta-analysis of anti-PD-1/PD-L1 regimens in advanced non-squamous NSCLC without EGFR or ALK alterations New drugs beat old ones for advanced lung cancer survival
This systematic review and network meta-analysis evaluated overall survival and progression-free survival across 15 Phase III randomized cli…
New drug combinations show better survival chances for advanced lung cancer patients whether their tumors express PD-L1 or not
Dry NaCl Inhalation Fails to Improve Mucociliary Clearance in COPD
Pulmonology & Critical Care RCT
Dry NaCl Inhalation Fails to Improve Mucociliary Clearance in COPD Inhaled salt fails to clear mucus in COPD trial
This randomized, placebo-controlled crossover study in 25 patients with GOLD stage I-III COPD found that a single 40 mg dry NaCl inhalation …
Inhaling dry salt did not improve mucus clearance in COPD patients, a small trial finds. The study was cut short by COVID-19.
Subcutaneous tislelizumab shows comparable trough concentrations to intravenous dosing in treatment-naive advanced non-small cell lung cancer patients
Pulmonology & Critical Care Phase I
Subcutaneous tislelizumab shows comparable trough concentrations to intravenous dosing in treatment-naive advanced non-small cell lung cancer patients Phase I trial shows subcutaneous tislelizumab reaches high drug levels in lung cancer patients
This phase I trial evaluated subcutaneous versus intravenous tislelizumab in treatment-naive patients with advanced non-small cell lung canc…
Early data suggest subcutaneous tislelizumab injections may offer similar drug levels to intravenous forms for treating advanced lung cancer…