HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Psychiatry
RCT
Adjunctive JNJ-42165279 fails to improve depression in SSRI/SNRI inadequate responders
Early trial finds new drug did not help depression in patients already on antidepressants
This phase 2a double-blind RCT tested adjunctive JNJ-42165279 25 mg daily versus placebo in 153 adults with major depressive disorder with a…
A small early study found a new drug did not improve depression symptoms for patients already taking standard antidepressants.
May 1, 2026
Nutrition & Obesity Medicine
Meta-analysis
Umbrella review identifies risk factors and protective factors for male infertility and semen quality
New study lists many things that hurt male fertility and health
This umbrella review of 43 studies synthesizes evidence on risk factors for male infertility and abnormal semen parameters.
A new review shows that obesity, smoking, and certain illnesses can hurt sperm, but healthy habits might fix the problem.
May 1, 2026
Drug Pipeline
Sys. Review
Systematic review of Traditional Chinese Medicine for depression with unreported outcomes and safety data
Ancient Herbs Show Promise for Hard-to-Treat Depression
This systematic review evaluates Traditional Chinese Medicine (TCM), including botanical drug formulas, single medicinal botanical drugs, an…
Scientists are finding that traditional herbal blends might help where modern pills fall short.
Frontiers
Apr 24, 2026