Semaglutide reduces insulin dose in adults with type 1 diabetes and obesity
Semaglutide Cuts Insulin Needs By Half In Type 1 Diabetes
A post hoc analysis of an RCT found that semaglutide 1 mg/week significantly reduced total daily insulin dose by 22.6% over 26 weeks in adul…
Semaglutide reduces insulin needs quickly in type 1 diabetes patients, offering a new hope for better blood sugar control and weight managem…
Narrative review of transposable element methylation in autoimmune diseases
Genetic elements may link autoimmune diseases to inflammation
This narrative review examines the role of transposable element (TE) methylation and expression in Type 1 diabetes, systemic lupus erythemat…
Changes in certain genetic elements could explain how the body triggers inflammation in diseases like lupus and rheumatoid arthritis.
Umbrella review identifies risk factors and protective factors for male infertility and semen quality
New study lists many things that hurt male fertility and health
This umbrella review of 43 studies synthesizes evidence on risk factors for male infertility and abnormal semen parameters.
A new review shows that obesity, smoking, and certain illnesses can hurt sperm, but healthy habits might fix the problem.
Meta-analysis finds slight IQ difference in children with type 1 diabetes versus peers
Children with diabetes show slightly lower IQ scores than peers
This meta-analysis of 16 studies examined cognitive outcomes in children and adolescents with type 1 diabetes.
New research shows kids with type 1 diabetes may have slightly lower IQ scores but large groups show no reading or language gaps
Barriers and promoters to CGM and AID use in youth with T1D and public insurance
New plan helps families with public insurance get life-saving diabetes tech
This prospective, mixed-methods study examined barriers and promoters to continuous glucose monitoring (CGM) and artificial insulin delivery…
A new study reveals why families with public insurance struggle to get diabetes tech and offers a custom plan to fix it.
Beta-cell stress responses contribute to early Type 1 diabetes development and disease progression
Type 1 Diabetes May Start Inside the Cell, Not Just the Immune System
This perspective and review of human tissue, single cell transcriptomics, and longitudinal cohort studies indicates that beta-cell stress re…
This study shifts the focus of Type 1 diabetes from a pure immune problem to a two-part story where stressed cells play a key role.
FDA Approves Tzield (teplizumab) to Delay Onset of Stage 3 Type 1 Diabetes
FDA approves Tzield to delay type 1 diabetes in high-risk patients
The FDA approved Tzield (teplizumab) to delay the onset of Stage 3 type 1 diabetes in patients aged 1 year and older with Stage 2 disease.
The FDA approved Tzield (teplizumab) to delay the onset of stage 3 type 1 diabetes in people aged 1 and older with stage 2 disease.
Meta-analysis of sex differences in insulin therapy outcomes for adults with Type 1 and Type 2 diabetes
Women and Men Respond Differently to Insulin Therapy
This systematic review and meta-analysis evaluated sex differences in insulin therapy outcomes across 24 studies involving adults with Type …
Maria takes insulin every day for type 2 diabetes.
Meta-analysis of adjunctive SGLT2 inhibitors in type 1 diabetes shows mixed safety and efficacy signals
No More Bone Fear With New Diabetes Drug
This meta-analysis evaluated adjunctive SGLT2 inhibitor therapy in 6,731 patients with type 1 diabetes mellitus receiving insulin-based ther…
Many people with type 1 diabetes worry about their bones.
Observational MRI study links impaired hypoglycemia awareness to blunted cerebral blood flow responses in type 1 diabetes
Type 1 Diabetes Rewires How the Brain Responds to Low Blood Sugar
This observational study used hyperinsulinemic clamp with arterial spin-labeling MRI to compare cerebral blood flow responses to hypoglycemi…
Type 1 diabetes changes how the brain handles low blood sugar, and those who can't feel the danger show the most severe disruption in brain …
Narrative review examines immune modulation strategies for beta-cell replacement in type 1 diabetes
Can changing the immune system help replace damaged cells in Type 1 diabetes?
This narrative review explores immune modulation strategies for beta-cell replacement, including graft-intrinsic immune engineering, local g…
New strategies aim to stop the immune system from attacking insulin cells, offering a potential path to replace damaged tissue in Type 1 dia…
Meta-analysis finds high prevalence of adverse outcomes in African women with hyperglycaemia in pregnancy
High Sugar in Pregnancy Risks C-Section in Africa
A systematic review and meta-analysis of 9,742 women with hyperglycaemia in pregnancy in Africa found high prevalence rates of caesarean sec…
High blood sugar during pregnancy in Africa significantly raises the risk of needing a C-section, threatening both mother and baby.