Case-Control Study Finds No Association Between G6PD Deficiency and Systemic Lupus Erythematosus Risk in Females
G6PD Deficiency Does Not Raise Lupus Risk
This case-control study compared G6PD deficiency rates in 516 female systemic lupus erythematosus patients versus 491 age-matched healthy fe…
Having G6PD deficiency does not make you more likely to develop systemic lupus erythematosus.
Meta-analysis links long-term glucocorticoid use and SLE duration to high osteoporosis prevalence in patients
Lupus Patients Face Hidden Bone Loss Risk
This systematic review and meta-analysis evaluated 59 studies involving patients with systemic lupus erythematosus (SLE) to assess bone heal…
Bone loss affects 1 in 6 lupus patients, a hidden risk often overlooked due to the disease and its treatments.
Case report details KFD patient developing SLE treated with immunosuppression
Your stomach hurts. You throw up. You think it is just food poisoning. But what if your immune system is fighting a hidden battle inside your lymph nodes? This story is about a rare condition that tricks doctors and changes a patient's life forever
This case report describes a single patient with Kikuchi-Fujimoto disease who subsequently developed systemic lupus erythematosus.
Severe stomach pain and vomiting from a rare immune disorder can hide a hidden battle in your lymph nodes that tricks doctors into missing t…
Systematic review links neutrophil extracellular trap dysregulation to pregnancy complications
Web of White Blood Cells Linked to Pregnancy Risks
A systematic review of emerging evidence indicates that dysregulation of neutrophil extracellular trap (NET) formation and clearance is stro…
A sticky web of white blood cells meant to fight germs can instead trigger serious pregnancy risks like preeclampsia and preterm birth when …
Anifrolumab shows higher remission rates versus placebo in SLE patients regardless of immunosuppressant history
A New Lupus Drug May Work Better If You Start It Sooner
A post hoc analysis of pooled Phase 3 RCT data in 726 patients with moderate-to-severe SLE found higher DORIS remission rates with anifrolum…
Starting a new lupus drug before trying older medications may help patients reach remission faster and with fewer side effects.
Hydroxychloroquine did not prevent SLE progression in incomplete lupus patients in randomized trial
Hydroxychloroquine did not slow disease progression in incomplete lupus patients over two years
A randomized, double-blind trial of 180 patients with incomplete lupus erythematosus found hydroxychloroquine did not reduce progression to …
Hydroxychloroquine failed to slow lupus progression in patients with early symptoms over two years, matching placebo results.
IFN-I signature correlates with alloimmunization transcriptomic programs in SLE patients
Could a common lupus signal reveal who's at risk for transfusion complications?
An observational cohort analysis of 150 SLE patients from three RNA-seq cohorts found a significant positive correlation between Type I inte…
A high Type I interferon signal in lupus patients strongly predicts genetic markers linked to dangerous immune reactions to blood transfusio…
Peer mentoring shows non-significant symptom reduction in African American women with SLE
Peer mentoring shows potential for lupus symptoms in African American women
A randomized controlled trial sub-analysis in adult African American women with SLE found that a 12-session peer-mentoring intervention led …
A study tested whether peer mentoring could help African American women with lupus manage their symptoms.
Meta-analysis finds elevated neutrophil-to-lymphocyte ratio in SLE, with weak correlation to disease activity
Can a simple blood test help track lupus activity? The evidence is mixed
A meta-analysis of 40 studies with external validation (n=290) found neutrophil-to-lymphocyte ratio (NLR) was higher in SLE patients versus …
A simple blood ratio tracks lupus activity better than healthy levels, but its accuracy varies by ethnicity and treatment, so it isn't ready…
LOC100130476 rs80213143 variant associated with SLE susceptibility and renal involvement in Chinese Han cohort
Genetic variant linked to lupus susceptibility and kidney involvement in Chinese study
A cohort study in a Chinese Han population found the rs80213143 variant at LOC100130476 was associated with systemic lupus erythematosus sus…
A specific genetic marker found in Chinese patients is strongly linked to lupus and predicts more severe kidney disease.
Review examines glucose metabolic reprogramming in SLE and lupus nephritis pathogenesis
Review explores how sugar metabolism changes might fuel lupus immune system problems
A systematic review synthesizes evidence on glucose metabolic reprogramming in immune cells in systemic lupus erythematosus and lupus nephri…
Lupus immune cells change how they use sugar for energy, a shift that drives the disease and kidney damage, opening doors to new metabolic t…
Perspective highlights diagnostic overlap between idiopathic multicentric Castleman disease and systemic lupus erythematosus
Castleman disease can resemble lupus, requiring careful diagnosis for proper treatment
A perspective article discusses the clinical resemblance between idiopathic multicentric Castleman disease (iMCD) and systemic lupus erythem…
Castleman disease often mimics lupus with shared symptoms and autoantibodies, but misdiagnosis risks wrong treatment until a lymph node biop…