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Neurology
Meta-analysis
Meta-analysis finds non-linear exercise dose-response for mobility in stroke patients aged 45+
Exercise dose matters for mobility in stroke patients, but optimal amounts vary by type
A Bayesian dose-response meta-analysis of 25 RCTs (n=788) in middle-aged and older adults with stroke found a non-linear association between…
Stroke patients gain the most mobility improvement at about 1400 minutes of weekly exercise, but the perfect amount depends on the specific …
Apr 9, 2026
Neurology
RCT
10 Hz rTMS over SMA enhances balance in stroke patients with balance disorders
Can magnetic pulses help stroke patients stand steadier and feel safer walking again?
This randomized controlled trial evaluated 10 Hz repetitive transcranial magnetic stimulation (rTMS) over the supplementary motor area in 40…
Ten sessions of magnetic brain stimulation helped stroke patients improve balance and stand steadier without serious side effects.
Apr 9, 2026
Geriatrics & Aging
Sys. Review
Stroke survivors face substantially increased hip fracture incidence and elevated mortality compared to non-stroke populations
Stroke Survivors Face High Risk of Broken Hips
This narrative review examines epidemiological and clinical interrelationships between stroke and hip fractures in stroke survivors over a 5…
A broken hip after a stroke is a dangerous double hit that kills faster and hurts more than in anyone else.
Frontiers
Apr 9, 2026
Neurology
Sys. Review
Plastic changes in brainstem reticular formation may be involved in spasticity onset across stroke and spinal cord injury
Could brainstem plastic changes trigger spasticity in stroke and spinal cord injury patients?
This systematic review examined pathophysiological similarities in spasticity among humans, primates, and rodents.
Spasticity after stroke or spinal cord injury may stem from plastic changes in the brainstem, though evidence remains limited and controvers…
Frontiers
Apr 9, 2026
Physical Medicine & Rehab
Soleus coordination deficits observed during standing in subacute stroke patients versus controls
Why is standing so hard after a stroke? A new clue lies in calf muscle timing
An observational study of 14 individuals undergoing subacute stroke rehabilitation and 16 matched controls found reduced bilateral synchroni…
After a stroke, calf muscles fire at the wrong time, but one week of rehab syncs them back up to improve balance.
medRxiv
Apr 8, 2026
Cardiology
Meta-analysis
DOACs show varied efficacy and safety profiles versus VKAs in atrial fibrillation patients with fall risk
Study compares blood thinners for atrial fibrillation patients with fall risk
A Bayesian network meta-analysis of 10 studies (5 RCTs, 5 observational) in AF patients with fall history/risk found apixaban ranked highest…
For atrial fibrillation patients at risk of falling, apixaban best prevents strokes while edoxaban best lowers major bleeding risks compared…
Apr 5, 2026
Neurology
Meta-analysis
Meta-analysis finds nonlinear dose-response between physical activity and reduced stroke risk
How much exercise protects against stroke? A new analysis finds the sweet spot
A meta-analysis of 14 prospective cohort studies with 2.6 million participants found nonlinear inverse associations between physical activit…
A new analysis of over 2.6 million people finds that moderate exercise—like a few vigorous workouts weekly—can cut stroke risk by up to 19%,…
Apr 5, 2026
Neurology
RCT
Cognitive training perspectives show no significant far transfer effects in acute stroke rehabilitation trial
Can changing how stroke patients think about space help their mood and movement?
A randomized clinical trial of 128 acute stroke patients found that adding allocentric or egocentric perspective cognitive training to conve…
Adding mental exercises to stroke rehab did not improve mood or movement compared to standard care alone in a study of 128 patients.
Apr 4, 2026
Diabetes & Endocrinology
Cohort
High body roundness index associated with higher odds of prevalent stroke in Chinese adults
Could a simple waist measurement help spot stroke risk in your community?
A cross-sectional study of 6,858 adults in a Chinese community screening program found high body roundness index (BRI ≥4.6) was associated w…
A simple waist measurement called the Body Roundness Index may help spot stroke risk in community screenings, though it works best alongside…
Frontiers
Apr 4, 2026
Neurology
RCT
Post hoc analysis finds cilostazol reduces stroke recurrence without lowering systolic blood pressure
Study finds cilostazol reduces stroke recurrence without lowering blood pressure
A post hoc mediation analysis of an RCT in 1,795 patients with noncardioembolic ischemic stroke found dual therapy with cilostazol plus…
Cilostazol lowers stroke recurrence risk in patients with prior noncardioembolic strokes without working by dropping their blood pressure.
Apr 3, 2026
Neurology
Phase II
ENGAGE program shows feasibility and preliminary signal for participation after chronic stroke in pilot trial
Can a peer-led program help stroke survivors reconnect with their communities?
A phase 2a single-arm pilot trial of 30 community-dwelling stroke survivors assessed a 6-week ENGAGE intervention co-facilitated by peer men…
A new stroke support program helped 30 survivors reconnect with their communities, showing high satisfaction and safe participation in socia…
Apr 3, 2026
Neurology
RCT
Bilateral training shows greater motor recovery than conventional therapy in subacute stroke patients
Small study finds bilateral training may help stroke patients' motor recovery
A randomized trial in 40 subacute stroke patients compared comprehensive bilateral training to conventional physiotherapy over 6 weeks.
Stroke patients who did physical therapy on both sides, not just the weakened one, saw slightly better leg recovery in a small trial.
Apr 3, 2026