HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Geriatrics & Aging
Cohort
Narrative review on mpMRI and PSMA PET/CT for radiorecurrent prostate cancer restaging
Two imaging tests together spot prostate cancer return more accurately
This narrative review synthesizes evidence on mpMRI and PSMA-targeted PET/CT for restaging radiorecurrent prostate cancer.
For men with suspected prostate cancer return, combining two scans catches more tumors and avoids unnecessary biopsies.
Frontiers
Apr 23, 2026
Drug Pipeline
RCT
Enzalutamide Monotherapy Shows Higher Survival and Metastasis-Free Rates Versus Leuprolide in High-Risk Biochemical Recurrence
Enzalutamide shows better outcomes than leuprolide for high risk prostate cancer recurrence
This Phase 3 randomized controlled trial evaluated enzalutamide monotherapy versus leuprolide alone in patients with high-risk biochemical r…
Men with high-risk prostate cancer recurrence lived longer and spread less cancer when taking enzalutamide alone instead of leuprolide alone…
Apr 19, 2026
Oncology
Cohort
Proton therapy shows dosimetric advantages over photon therapy for prostate cancer treatment
Can proton therapy spare healthy tissue better for prostate cancer patients?
This review summarizes evidence on proton therapy for prostate cancer across treatment settings.
Proton therapy spares healthy tissue better than standard radiation for prostate cancer, offering excellent disease control with low rates o…
Frontiers
Apr 19, 2026
Oncology
Cohort
Multimodal CNN outperforms PSA alone for prostate cancer diagnosis in biopsy-confirmed patients
New MRI tool may improve prostate cancer diagnosis compared to PSA alone
This retrospective cohort study evaluated 305 patients with PSA levels 4–10 ng/mL who underwent multiparametric MRI and biopsy.
A new AI tool analyzing MRI scans correctly identified prostate cancer in 85.3% of cases and ruled it out in 90.9%, far outperforming PSA bl…
Frontiers
Apr 17, 2026
Oncology
RCT
Prolonged nightly fasting plus telehealth coaching showed feasibility in men with prostate cancer on androgen deprivation therapy
Can fasting and coaching help men with prostate cancer feel better and manage weight?
This pilot randomized controlled trial assessed a prolonged nightly fasting plus telehealth coaching intervention (PNF+) versus healthy eati…
Men with prostate cancer on treatment safely tried nightly fasting and coaching, improving quality of life and showing slight weight loss wi…
Apr 16, 2026
Oncology
Cohort
Multimodal AI applications in urologic oncology for prostate, bladder, and kidney cancers
Smarter Cancer Care: How AI Is Learning to See the Whole Picture
This narrative review examines multimodal artificial intelligence (AI) applications in urologic oncology for patients with prostate, bladder…
New AI tools combine scans, biopsies, and genes to give clearer answers for prostate, bladder, and kidney cancer patients, though most are s…
Frontiers
Apr 15, 2026
Rheumatology
Meta-analysis
Meta-analysis of [99mTc]Tc-PSMA SPECT/CT detection rates in prostate cancer staging and restaging
Cheaper Scan Finds Cancer Where PET Can't Reach
This systematic review and meta-analysis evaluated [99mTc]Tc-PSMA SPECT/CT in 1,840 patients with prostate cancer.
A cheaper prostate cancer scan finds tumors where expensive PET machines can't reach, offering hope for clinics in smaller towns.
Frontiers
Apr 13, 2026
Oncology
Sys. Review
Case report describes embolization and endocrine therapy for post-biopsy hematoma in prostate cancer patient
A Rare Bruise After Prostate Biopsy — What Every Man Should Know
A case report and literature review describes a prostate cancer patient who developed extensive subcutaneous hematoma after transperineal pr…
Large bruising after prostate biopsy is uncommon, but knowing how it looks can get treatment started quickly.
Frontiers
Apr 13, 2026
Oncology
Cohort
Quantitative MRI and clinical data model predicts prostate cancer in patients with lesions
A Smarter MRI Read May Spot Prostate Cancer Without a Biopsy
A retrospective cohort study of 290 patients with prostate lesions found that a prediction model integrating multimodal quantitative MRI and…
A new MRI scoring tool accurately spots prostate cancer in men facing biopsy decisions, potentially sparing them from painful, unnecessary n…
Frontiers
Apr 13, 2026
Urology
Cohort
AI model shows high accuracy for prostate cancer and prostatitis detection on MRI in retrospective cohort
AI models showed promise in detecting prostate conditions but need more testing
A retrospective cohort study of 153 patients with prostate cancer or prostatitis found that a Faster R-CNN model achieved 96% accuracy for P…
AI models matched expert doctors in reading prostate MRI scans but missed smaller cancer lesions, showing promise that needs more testing be…
Frontiers
Apr 13, 2026
Urology
Phase I
Ga-PSMA-11 PET/CT shows high sensitivity for local prostate cancer but lower for lymph nodes in phase 1/2 trial
Imaging test shows promise for detecting prostate cancer spread in early trial
A prospective phase 1/2 single-arm trial in 173 high-risk prostate cancer patients found Ga-PSMA-11 PET/CT had 0.971 sensitivity for local d…
A new imaging test found prostate cancer in lymph nodes for 56% of patients, leading doctors to cancel surgery for 13% and adjust radiation …
Apr 13, 2026
Primary Care & Family Medicine
Sys. Review
Systematic review finds PSA screening reduces prostate cancer mortality but increases overdiagnosis and false positives
A New Prostate Cancer Check Could Save Lives—With Fewer False Alarms
A systematic review and meta-analysis of men not known to be at high risk for prostate cancer found that PSA-based screening likely reduces …
A new analysis of nearly a million men shows adding an MRI after a high PSA test drastically cuts false alarms and unnecessary biopsies.
medRxiv
Apr 11, 2026