Systematic review and meta-analysis compares micro-ultrasound and mpMRI guidance for prostate biopsy cancer detection
Micro-ultrasound guidance finds prostate cancer at same rate as MRI
This systematic review and meta-analysis evaluated clinically significant and insignificant prostate cancer detection rates between micro-ul…
A large analysis found micro-ultrasound and MRI guidance detect prostate cancer equally well during biopsy, offering a viable alternative fo…
PSA levels at 6, 12, and 24 weeks post-randomization correlate with 96-month survival in prostate cancer
Low PSA at 24 weeks predicts longer survival in prostate cancer
This post-hoc analysis of five phase 3 trials in 7129 patients with prostate cancer found that 96-month overall survival varied by metastati…
Men with prostate cancer who hit a PSA level of 0.2 ng/mL or less within 24 weeks of starting treatment are far more likely to survive at le…
Meta-analysis of artificial intelligence models for predicting prostate cancer outcomes
AI Predicts Prostate Cancer Outcomes With 80 Percent Accuracy
This meta-analysis evaluated 85 studies regarding the performance of artificial intelligence models in predicting various prostate cancer ou…
New AI tools can predict prostate cancer outcomes with over 80 percent accuracy, helping men and their doctors make better treatment decisio…
PHS601-based stratification increases prostate cancer risk estimates in Norwegian population-based cohorts
Genetic test shows higher prostate cancer risk in specific groups
This cohort study evaluated PHS601-based stratification in Norwegian population-based cohorts.
A genetic test linked to prostate cancer risk found that men in the top 1.8 percent of scores faced nearly nine times higher risk than avera…
MRI-RSI changes during neoadjuvant ADT and radiotherapy in men with high-risk localized prostate cancer
Early MRI scans shrink after treatment to help spot prostate cancer recurrence sooner
This prospective phase II trial protocol reports early results from 97 men with unfavorable-intermediate-risk or high-risk localized prostat…
New MRI scans taken before and during treatment for prostate cancer show clear shrinkage that could help doctors target the tumor more accur…
Narrative review evaluates urine-based PSMA detection technologies as emerging noninvasive diagnostics for prostate cancer
Urine Test for Prostate Cancer Could Cut Unnecessary Biopsies
This narrative review examines urine-based PSMA detection technologies, including antibody-based immunoassays and CRISPR/Cas12a-assisted sig…
A urine test that spots a prostate cancer protein may soon make screening safer and more accurate for millions of men.
Umbrella review associates processed meat consumption with higher risks of cancer and chronic disease outcomes
Processed meat links to higher cancer and heart disease risks
This umbrella review synthesized data from 34 articles and 54 meta-analyses regarding processed meat consumption.
Eating more processed meat like bacon or hot dogs increases your risk for serious health problems including cancer and heart disease.
Machine learning quantification of Gleason Pattern 4 showed higher discrimination for adverse pathology than grade group in prostate cancer
AI Measures Prostate Cancer Risk More Accurately Than Standard Methods
This proof-of-principle cohort study evaluated 726 patients with grade group 2-4 prostate cancer on systematic biopsy who underwent radical …
A new AI tool can spot dangerous prostate cancer patterns better than current grading, offering men a clearer picture of what to expect afte…
Preclinical deep learning framework shows improved dose prediction for unseen cancer sites
A Heavy Burden on Doctors
This is a preclinical development study of a deep learning framework for radiotherapy dose prediction.
A new AI tool can plan radiation doses for many different cancers at once.
Transdermal Estradiol Patches Show Noninferiority to LHRH Agonists in Prostate Cancer Metastasis-Free Survival
Men with advanced prostate cancer may have fewer hot flashes with a new patch treatment
This phase 3 randomized trial evaluated 1360 men with locally advanced prostate cancer across 75 U.K.
A new patch for advanced prostate cancer showed similar cancer control to standard shots but caused fewer hot flashes in a large UK trial.
Narrative review offers practical recommendations for implementing PET-guided therapy workflows in clinical practice
PET scans now guide your radiation treatment
This narrative review synthesizes evidence regarding the implementation of PET-guided therapy workflows.
Imagine standing in a doctor's office waiting for radiation therapy.
Image-guided radiotherapy dose intensification for intermediate- or high-risk prostate cancer
New prostate cancer radiation targets only the tumor, not the whole gland
This is a phase II randomized controlled trial protocol for patients with intermediate- or high-risk prostate cancer planning radiotherapy.
This study tests a smarter way to deliver radiation—focusing the dose on the tumor while protecting the rest of the prostate, which could me…