Wholegrain rye diets improve metabolic markers but not weight loss in overweight adults
Wholegrain rye lowers inflammation better than refined wheat for weight loss diets
This 12-week randomized trial compared hypocaloric diets with wholegrain rye versus refined wheat in 255 adults with overweight or obesity.
Switching to wholegrain rye while dieting may lower inflammation and improve gut bacteria even if weight loss is the same
Oral Sodium Butyrate Reduces Weight in Overweight Adults Without Diabetes
Oral sodium butyrate helps overweight adults without diabetes lose weight
This 12-week proof-of-concept RCT in 46 overweight adults (23 with type 2 diabetes) found that oral sodium butyrate 1875 mg/day led to great…
A new trial shows oral sodium butyrate helps adults without diabetes lose more weight than a placebo over three months.
Extended sleep improved sleep metrics but did not change insulin sensitivity in a small trial
Extended sleep improves sleep duration but not insulin sensitivity in small trial
This randomized trial investigated whether extending sleep duration improves metabolic health in people with overweight or obesity and habit…
In a small trial, people with overweight or obesity who slept longer stayed in bed more and felt better, but insulin sensitivity did not imp…
Afternoon/Evening Exercise May Lower Blood Pressure More Than Morning Exercise: Meta-Analysis
Evening exercise lowers blood pressure and sugar better than morning workouts for people with diabetes or high weight
This systematic review and meta-analysis of 625 participants found that afternoon/evening exercise (PmEx) was associated with significantly …
For people with type 2 diabetes or high blood pressure, working out in the afternoon or evening lowers blood pressure and sugar more than mo…
Bayesian network meta-analysis compares exercise modalities for systemic inflammation in postmenopausal women
Resistance training reduces inflammation in postmenopausal women
This Bayesian network meta-analysis of 39 RCTs evaluated the comparative efficacy of aerobic, resistance, HIIT, and combined training on inf…
New evidence suggests different types of exercise target different inflammatory markers in postmenopausal women with obesity.
GZR18 showed weight loss in Chinese adults with overweight or obesity in a phase 1b/2a trial
New Drug Cuts Weight by Nearly 20% in Just 35 Weeks
In this randomized, placebo-controlled phase 1b/2a trial, 60 Chinese adults with overweight or obesity received GZR18 or placebo.
This new treatment shows huge promise for helping people reach their weight goals without daily pills.
Tirzepatide MTD Demonstrates Cost-Effectiveness Versus Semaglutide MTD in Obesity Simulation Modeling Study
Tirzepatide Saves Money and Health Over Semaglutide
This simulation modeling study using Phase-3 trial data evaluated tirzepatide versus semaglutide in individuals with obesity or overweight w…
Imagine standing in a doctor's office, facing a choice between two powerful weight-loss medicines.
Meta-analysis links ultra-processed food intake to higher odds of adolescent overweight/obesity
High ultra-processed food intake linked to higher obesity risk in teens
This systematic review and meta-analysis synthesizes evidence on ultra-processed food consumption and overweight/obesity in adolescents.
Teens who eat lots of ultra-processed foods have 63% higher odds of being overweight or obese compared to those with lower intake.
Theory-informed behavioural intervention reduces ultra-processed food intake and weight in UK adults
You Can Eat Better And Lose Weight By Swapping Foods
This exploratory single-arm pre-post study in 45 UK adults with overweight or obesity and habitual ultra-processed food (UPF) intake of at l…
A new plan to swap processed snacks for real food helps people lose weight and feel better.
Network meta-analysis finds metabolic surgery superior to GLP-1 agonists for weight loss in obesity
Weight-Loss Surgery Still Leads, But a New Medication Closes the Gap
A network meta-analysis of 20,015 adults with overweight or obesity compared metabolic/bariatric surgery, GLP-1 receptor agonists, and lifes…
Weight-loss surgery still beats drugs overall, but the newest medication tirzepatide closes the gap enough to matter for people who can't ha…
Post-hoc analysis finds both continuous and intermittent calorie restriction reduce weight in type 2 diabetes
Two calorie-restricted diets helped people with type 2 diabetes lose weight in a small study
A post-hoc analysis of RCTs in 67 people with type 2 diabetes and overweight or obesity compared 3-month continuous vs.
Two calorie-restricted diets helped people with type 2 diabetes lose weight and reduce fat while gaining muscle in a new study.
Overweight status at diagnosis in Kuwaiti children with new-onset type 1 diabetes is associated with milder clinical presentation and lower HbA1c
Overweight Kids With Diabetes Have Milder Symptoms
This retrospective cohort study analyzed 1,265 children aged 14 years or younger newly diagnosed with type 1 diabetes in Kuwait.
Being overweight changes how type 1 diabetes starts in children, making the early stage look different and easier to manage initially.