Mycophenolate mofetil non-inferior to prednisone for first-episode nephrotic syndrome in children
Mycophenolate Mofetil Offers Alternative to Steroids for Nephrotic Syndrome
This phase 3 non-inferiority trial randomized 272 children aged 1-10 years with first-episode steroid-sensitive nephrotic syndrome to mycoph…
A new trial shows mycophenolate mofetil works as well as prednisone for children with nephrotic syndrome, with fewer steroid side effects.
Obesity associated with reduced SLE relapse rates in Japanese registry cohort
A Surprising Link Between Weight and Lupus Flares
This observational cohort study of 1134 patients with systemic lupus erythematosus in Japan found that obesity (BMI ≥25 kg/m2) was associate…
Being overweight or mildly obese might lower the risk of lupus relapses, challenging common beliefs about weight and autoimmune disease.
Prednisolone plus standard treatment did not significantly reduce coronary-artery lesions in newly diagnosed Kawasaki disease patients
Adding prednisolone to standard care did not prevent heart damage in Kawasaki disease patients
This multicenter, open-label, randomized, controlled trial evaluated 3208 participants with newly diagnosed Kawasaki disease in China.
Adding prednisolone to standard care did not prevent heart damage in Kawasaki disease patients, as lesion rates remained nearly the same.