Interstitial lung disease reduces achievement of rheumatoid arthritis treatment goals over 24 months
Why Interstitial Lung Disease Blocks Rheumatoid Arthritis Goals
This retrospective cohort study examined 254 patients with newly diagnosed rheumatoid arthritis who underwent chest CT within one year of on…
Rheumatoid arthritis treatments often fail to reach pain-free goals when the disease also attacks the lungs, making standard care harder for…
Biological DMARDs show marginal patient-reported outcome benefits over conventional therapy in early rheumatoid arthritis
Early rheumatoid arthritis patients report similar symptom relief with different treatment approaches
This open-label randomized trial in 795 newly diagnosed, DMARD-naïve RA patients compared three biological DMARDs plus methotrexate against …
In early rheumatoid arthritis, patients reported similar pain relief and quality-of-life improvements whether they started with conventional…
Post-hoc analysis of RCTs and cohorts identifies predictors of remission in ACPA-positive early RA treated with abatacept plus methotrexate or methotrexate alone
Early disease activity and response predict remission in ACPA-positive rheumatoid arthritis patients
This post-hoc analysis of randomized controlled trials and an observational cohort evaluated predictors of DAS28-CRP remission in ACPA-posit…
Only early disease activity and treatment response predict remission in ACPA-positive rheumatoid arthritis, while genetic markers and imagin…
Hand massage improves grip strength and function in early RA patients in pilot trial
Can hand massage improve grip strength and reduce pain in early rheumatoid arthritis?
A pilot randomized controlled trial of 30 female RA patients with low disease activity found that 10 hand massage sessions over 2 weeks sign…
Ten hand massage sessions boosted grip strength and lowered pain for women with early rheumatoid arthritis, while standard care alone showed…
Cross-sectional study finds association between autoimmune thyroiditis and rheumatoid arthritis
Could a common thyroid condition be linked to rheumatoid arthritis?
A cross-sectional analysis of NHANES data (n=5,715) and an external clinical cohort (n=196) found autoimmune thyroiditis was significantly a…
People with autoimmune thyroiditis are more likely to have rheumatoid arthritis, with uric acid levels playing a modest role in the connecti…
Phase 2 trial finds hydroxychloroquine does not prevent rheumatoid arthritis in at-risk individuals
Hydroxychloroquine did not prevent rheumatoid arthritis in at-risk individuals in trial
In a phase 2 randomized controlled trial of 144 individuals at risk for rheumatoid arthritis with elevated anti-CCP3 antibodies, 12 months o…
A new trial found that taking hydroxychloroquine for a year did not stop people at high risk for rheumatoid arthritis from developing the di…
Occupational inhalant exposures associated with increased rheumatoid arthritis risk in meta-analysis
Study links workplace dust and chemical exposure to higher rheumatoid arthritis risk
A systematic review and meta-analysis of 31 studies found significant associations between occupational inhalant exposures and increased rhe…
Breathing workplace dust and chemicals like silica and asbestos may raise your risk of developing rheumatoid arthritis, according to a revie…
Rheumatoid arthritis is associated with a 58% higher risk of COPD compared to the general population
Rheumatoid Arthritis Patients Face Higher Risk of Developing Chronic Lung Disease
This systematic review and meta-analysis evaluated 1,710,600 individuals to assess the prevalence and risk of chronic obstructive pulmonary …
People with rheumatoid arthritis face a significantly higher risk of developing chronic obstructive pulmonary disease compared to the genera…
FPGS Gene Variants Linked to Methotrexate Efficacy and Toxicity in Rheumatoid Arthritis
Could your genes explain why methotrexate works better for some people?
A meta-analysis of 2345 rheumatoid arthritis patients on methotrexate found FPGS polymorphisms rs10106 and rs1544105 were significantly asso…
Your genes might explain why methotrexate works better for some rheumatoid arthritis patients but also raises their risk of harmful side eff…
Meta-analysis finds oral JAK inhibitors increase HDL and LDL cholesterol levels in patients from RCTs
Common arthritis and skin drugs linked to cholesterol changes, analysis finds
A systematic review and meta-analysis of 13 phase 2 and 3 RCTs involving 5,658 patients found treatment with oral JAK inhibitors (baricitini…
Common arthritis and skin drugs can raise both 'good' and 'bad' cholesterol levels, a review of nearly 4,000 patients shows.
Reduced anti-CXCR3 antibodies associated with systemic autoimmunity and atherosclerosis in cohort study
Study finds link between specific antibody levels and heart disease risk in autoimmune conditions
An observational cohort study of patients with rheumatoid arthritis, Sjogren disease, and controls found reduced anti-CXCR3 antibody levels …
Low levels of a specific antibody in early arthritis and joint pain are linked to higher heart disease risk and poorer medication responses.
Immune signatures precede and accompany subclinical joint inflammation in ACPA-positive individuals at high risk for RA
Study finds immune changes in blood may signal early joint inflammation before rheumatoid arthritis
An observational study of ACPA-positive individuals at high risk for rheumatoid arthritis used single-cell transcriptomics and proteomics to…
Blood tests reveal specific immune cell changes that signal joint inflammation is starting before rheumatoid arthritis symptoms appear.