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Genetics & Precision Medicine
Phase I
Genomically tailored multiagent regimen shows limited efficacy in recurrent glioblastoma
Personalized drug combos extend life in brain cancer
This phase I trial tested a genomically tailored multiagent regimen in 30 adults with recurrent glioblastoma. Median overall survival was 12…
A new approach using tailored drug combinations is helping some patients with recurring brain cancer live longer, offering fresh hope where …
May 1, 2026
Oncology
Phase I
LP-184 Alone and With Spironolactone in Recurrent Glioblastoma: Phase 1a Results
New drug combo may help brain cancer patients who have run out of options
This Phase 1a trial in 63 patients (16 with glioblastoma) found LP-184 was well tolerated but with more transaminitis and thrombocytopenia i…
A new drug combination could help brain cancer patients by making their current medicine work much harder inside the tumor.
medRxiv
Apr 25, 2026