Systematic Review Examines T-Cell Mechanisms and Therapies in Multiple Sclerosis
New Review Looks At Multiple Sclerosis Treatments And Immune System Mechanisms
This systematic review addresses multiple sclerosis, focusing on T-cell-mediated immunodysregulation mechanisms, disease-modifying therapies…
Multiple sclerosis, a leading cause of disability in young people, involves T-cell immune responses that drive inflammation and are targeted…
Real-world cohort examines Alemtuzumab effects on bowel/bladder function and latent progressive trajectories in MS patients
Did you know MS patients hide worsening symptoms that doctors might miss for years?
This real-world cohort study involving 1,025 MS patients utilized a trajectory-based statistical approach to analyze disease progression.
Doctors might miss worsening MS symptoms for years because patients hide them, but a new method found over 11,000 hidden patterns in real-wo…
EBV DNA positivity links to MS risk genes in a cross-ancestry study of 617,186 participants
A Common Virus May Hold the Key to MS — Here's Why
This cross-ancestry genome-wide association study analyzed 617,186 individuals to investigate the relationship between Epstein-Barr virus (E…
A virus almost everyone carries may quietly flip immune switches that set off multiple sclerosis by altering how B cells signal to T cells.
REDDI pipeline improves balanced accuracy for classifying MCI, MS, Parkinson's, and ALS using MEG data
Can a new computer tool help doctors spot brain diseases faster and more accurately?
This study developed a machine learning framework called REDDI that utilizes MEG resting-state data and Riemannian geometry for classifying…
A new computer tool helps doctors distinguish between hard-to-tell-apart brain diseases like Parkinson's and ALS with 13% better accuracy.
Home-based e-based exercise protocol feasibility study for patients with multiple sclerosis and comorbidities
Working Out From Home Could Slow Multiple Sclerosis Progression
This protocol describes a home-based e-based physical exercise program for patients with multiple sclerosis (pwMS) with and without comorbid…
A new trial tests if twice-weekly online resistance exercise from home can improve walking ability and reduce disease activity in people wit…
Rituximab exposure is associated with serum sickness in patients with multiple sclerosis, nephrotic syndrome, or immune thrombocytopenia
Can taking Rituximab cause a severe allergic reaction that returns if you take it again?
This retrospective review analyzed 39 published case reports of patients with rituximab-induced serum sickness (RISS).
Taking Rituximab can trigger a delayed allergic reaction that returns in most patients if the drug is given again, so doctors must use extre…
Network meta-analysis of six exercise modalities in females with multiple sclerosis shows improvements in fatigue, quality of life, balance, depression, and mental health
Which Workout Helps MS Most? The Winner Surprised Researchers
This network meta-analysis evaluated six distinct training programs or exercise modalities in females with multiple sclerosis compared to co…
Almost any regular movement helps women with MS, but yoga pulled ahead for fatigue and emotional well-being while classic aerobics won on ba…
Chiropractic thoracic spinal manipulation showed moderate effects on cytokines in a pilot RRMS trial
Spinal tweak lowers inflammation in MS patients
This randomized, sham-controlled pilot study enrolled 21 participants with relapsing-remitting multiple sclerosis.
A spinal tweak combined with muscle therapy lowered inflammation markers in people with multiple sclerosis, offering a new way to calm the i…
Respiratory muscle training improves respiratory muscle strength and pulmonary function in multiple sclerosis patients
A Simple Breathing Exercise May Strengthen a Core MS Symptom
This systematic review and meta-analysis evaluated respiratory muscle training (RMT) in 542 individuals with multiple sclerosis compared to …
Strengthening the muscles used to breathe can directly improve respiratory function for people with multiple sclerosis, offering a new layer…
Cladribine tablets maintain stable patient-reported outcomes in highly active MS over 52 weeks
Your Fitness Tracker Could Now Help Manage Your Multiple Sclerosis
An interim analysis of a prospective observational study in 190 Italian patients with highly active MS found that cladribine tablets maintai…
Multiple sclerosis patients using cladribine tablets maintain physical function while wearables track symptoms continuously between doctor v…
Sex differences in disability and demographics observed in a Swiss Multiple Sclerosis Cohort
MS Hits Men and Women Differently. Here’s What That Means for You
This cross-sectional analysis of 1,541 patients with relapsing-remitting or progressive multiple sclerosis examined sex differences in disab…
Multiple sclerosis starts earlier in women and disability builds differently in men, meaning treatment plans must account for these sex diff…
China's rehabilitation needs for neurological disorders increased significantly from 1990 to 2021
A Silent Wave of Disability is Rising. Here’s Who’s Most at Risk
This cross-sectional analysis of data from China between 1990 and 2021 examined rehabilitation needs for ten neurological conditions, includ…
China faces a rising wave of neurological disability driven by aging, with stroke, Alzheimer's, and Parkinson's creating urgent long-term ca…