GERD Associated with Increased Risk of Laryngeal Cancer in Meta-Analysis
Large study links GERD to higher risk of laryngeal cancer
A systematic review and meta-analysis of 1,768,394 adults found that gastroesophageal reflux disease (GERD) was significantly associated wit…
A massive analysis of nearly 1.8 million adults found a link between gastroesophageal reflux disease and increased risk of laryngeal cancer.
SIB-RT plus S-1 improves survival in elderly inoperable esophageal cancer
Combination therapy improves survival in older esophageal cancer patients
This phase III multicenter RCT compared simultaneous integrated boost radiotherapy plus oral S-1 (CRTCT) to radiotherapy alone in patients a…
Adding chemo to radiation boosts 5-year survival from 24% to 34% in older patients with inoperable esophageal cancer.
Review of multimodal deep learning model for esophageal squamous cell carcinoma diagnosis
New AI tool spots esophageal cancer early with expert accuracy
This review synthesizes a model development and validation study for esophageal squamous cell carcinoma.
A new AI system matches expert doctors in spotting early esophageal cancer. This could change how patients get diagnosed.
Deep learning segmentation with CT elasticity features predicts right recurrent laryngeal nerve metastasis in esophageal cancer
AI Can Spot Hidden Cancer Spread in the Neck Before Surgery
This retrospective cohort study of 415 patients with esophageal squamous cell carcinoma evaluated a deep learning-based segmentation model w…
This research could help surgeons avoid damaging a vital nerve during esophageal cancer surgery, making operations safer and more precise.
Neoadjuvant Chemoimmunotherapy Alters Tumor Microenvironment in Esophageal Cancer
Combination therapy may help overcome resistance in esophageal cancer
This Phase 3 RCT in 55 patients with locally advanced esophageal squamous cell carcinoma compared neoadjuvant chemotherapy alone versus comb…
A small trial suggests combination therapy might help overcome resistance in esophageal cancer by targeting specific immune cells.
Timing of surgery after neoadjuvant chemoimmunotherapy impacts survival in operable esophageal squamous cell carcinoma
Shrink Faster, Live Longer: Timing Saves Lives in Esophageal Cancer
This multicenter retrospective cohort study evaluated 163 patients with operable esophageal squamous cell carcinoma receiving neoadjuvant…
Faster tumor shrinkage and surgery within six weeks of treatment predict longer survival for esophageal cancer patients receiving new therap…
PD-1 inhibitors + chemo improve OS, PFS, ORR in first-line advanced ESCC; benefit limited in PD-L1 CPS <1
Who benefits most from new esophageal cancer treatment? Most patients do, except one group
A meta-analysis of 8 RCTs (n=4702) found first-line PD-1 inhibitors plus chemotherapy significantly improved OS (HR=0.68, 95% CI: 0.63-0.74;…
For most advanced esophageal cancer patients, adding immunotherapy to chemotherapy extends life and shrinks tumors, but those with low PD-L1…