Pilot study examines salivary adiponectin receptor expression in opioid-exposed neonates
How does a mother's opioid use affect her baby's growth signals?
This observational pilot cohort compared salivary adiponectin receptor 1 expression and growth measurements in neonates born at ≥34 weeks' g…
Doctors are investigating how a mother's opioid use during pregnancy might change a newborn's growth signals and body fat levels.
Neonatal EHR data from first 90 days shows limited prediction of neuropsychiatric diagnoses by age seven
Can a baby's first 90 days of medical data predict future brain health?
A retrospective cohort study of 17,655 neonates requiring intensive care found that a STraTS model using longitudinal neonatal EHR data achi…
A computer model analyzed early medical records to find five specific factors that signal higher risk for future autism or ADHD diagnoses by…
Delayed consultation and sickle cell disease associated with poor outcomes in pediatric osteomyelitis in Cameroon
Study in Cameroon finds delayed care linked to worse bone infection outcomes in children
A retrospective cross-sectional study of children with hematogenous osteomyelitis at five referral hospitals in Douala, Cameroon, found dela…
Children in Cameroon who waited over three months for care faced much higher risks of chronic infections, lasting problems, and long antibio…
Normal saline preservation solution increases serum sodium and blood pressure versus half saline in critically ill pediatric patients
Study in critically ill children compares two IV fluid types for sodium and blood pressure effects
A double-blind RCT of 88 critically ill pediatric patients in a PICU compared normal saline (0.9% sodium chloride) to half saline (0.45% sod…
Normal saline raises sodium and blood pressure more than half saline in critically ill children, guiding safer fluid choices for recovery.
Systematic review finds TF-CBT most supported for trauma in children under 12
Review compares 12 therapies for trauma symptoms in young children
A systematic review and partial meta-analyses of 127 studies involving 5689 trauma-exposed children ≤12 years found TF-CBT to be the most em…
Trauma-Focused Cognitive Behavioral Therapy is the most supported treatment for young children with trauma, while five other therapies lack …
Machine learning model predicts delayed methotrexate clearance in pediatric osteosarcoma patients
Study develops model to predict delayed drug clearance in pediatric bone cancer
A retrospective cohort study of 181 pediatric osteosarcoma patients treated with high-dose methotrexate developed a web-based prediction mod…
A new computer model predicts which children with bone cancer face delayed drug clearance, helping doctors monitor treatment risks before co…
Meta-analysis finds medium-sized negative association between body dissatisfaction and life satisfaction
Body dissatisfaction linked to lower life satisfaction across ages, large analysis finds
A preregistered meta-analysis of 62 observational studies with 195,548 participants found a robust, medium-sized negative association betwee…
Feeling bad about your body consistently lowers overall life satisfaction across all ages, a massive analysis of nearly 200,000 people confi…
Meta-analysis finds pediatric epilepsy associated with multidimensional sleep architecture abnormalities
Children with epilepsy show more sleep problems than healthy peers, review finds
A systematic review and meta-analysis of 24 studies in pediatric populations with epilepsy found significantly higher sleep disturbance scor…
Children with epilepsy face more sleep problems than healthy peers, including less efficient rest and lower REM sleep vital for learning.
Pilot RCT finds oxygen therapy trial feasible for children with pneumonia and hypoxaemia in Malawi
Small pilot study tests oxygen therapy feasibility for children with pneumonia in Malawi
A pilot randomized controlled trial of 21 children aged 1-59 months with pneumonia and SpO2 90-93% in Malawi assessed the feasibility of com…
A pilot study in Malawi found that testing three oxygen treatments for sick children was practical, with doctors following the plan closely …
Lung ultrasound scores higher in children with moderate-to-severe BPD; abnormal scores may aid readmission risk assessment
Lung ultrasound scores differ in children with severe bronchopulmonary dysplasia
A cross-sectional cohort study of 125 children aged 0–24 months found higher lung ultrasound scores in those with Grade 2 and 3 bronchopulmo…
A single lung ultrasound can spot breathing trouble risks in children with severe lung disease, though normal scans do not rule out the cond…
Plasma p-tau217 shows no correlation with age or comorbidity in adolescents
A key Alzheimer's marker doesn't change with age in teens, study finds
A cohort study of 41 adolescents found plasma p-tau217 did not correlate with age or BMI z-score and showed no differences by comorbidity or…
A new blood test for Alzheimer's shows wildly different results depending on whether blood is drawn from a vein or a finger prick in teens.
Conservative treatment shows favorable outcomes in five children with traumatic duodenal intramural hematoma
Small study describes imaging approach for children with rare intestinal injury
A retrospective cohort study of five children with traumatic duodenal intramural hematoma found that all were diagnosed by CT showing charac…
Doctors used CT scans and ultrasound to treat five children with a rare intestinal blood clot without surgery, achieving good outcomes.