This evidence summary reviewed 13 articles, including guidelines, expert consensuses, and evidence summaries, to compile best practices for managing nebulization in adult patients receiving nasal high-flow oxygen therapy. The review included one clinical decision, two guidelines, one team standard, seven expert consensuses, and two evidence summaries.
The analysis found that evidence levels ranged from Level 1 to Level 5, with recommendation grades of A (strong) and B (weak). The three guidelines and standards scored above 60% across all domains in a quality appraisal, and most items in the seven expert consensuses were rated positively.
No safety concerns were reported in the included documents. The main reason to be careful is that this is a compilation of existing guidance and not new research, so the recommendations are based on varying levels of evidence.
Readers should understand this summary provides a structured reference to guide the nebulization process, but it does not replace individual clinical judgment or new research findings.