This narrative review examined 91 studies involving women with endometriosis, deep infiltrating endometriosis, or adenomyosis who were undergoing assisted reproductive technologies. The authors looked at how different conditions affect oocyte yield, embryo quality, live birth rates, and miscarriage risks. They also considered the impact of treatments like gonadotropin-releasing hormone analogues and whether fresh or frozen embryo transfers work better.
The findings show that oocyte yield and embryo quality were reduced in some cases. Live birth rates were comparable to other infertility causes, but adenomyosis showed negative effects, especially when the disease was diffuse or severe. In contrast, frozen embryo transfer cycles appeared beneficial for women with endometriosis. For adenomyosis, outcomes were similar to fresh cycles.
Safety concerns were not reported in the review. However, the evidence regarding hormone analogue treatment and the choice between fresh and frozen transfers is inconsistent. Readers should note that IVF outcomes in adenomyosis remain controversial. Standardized screening with ultrasonography and MRI is recommended before starting treatment.