Medical Reviewer
Dr. Sofia Müller, MD
Lifespan & Whole-Person Care — Population health, longitudinal cohorts, care-delivery and goals-of-care research.
Dr. Sofia Müller is a freelance medical writer and physician based in Basel, Switzerland, specializing in Lifespan & Whole-Person Care with over 9+ years of combined clinical and medical writing experience. She holds an MD from the University of Zurich and is board-certified in Internal Medicine and Geriatrics. She also holds additional training in public health, palliative care, and clinical epidemiology.
Sofia focuses on population health research, longitudinal cohort studies, and care delivery models across pediatrics, women's health, geriatrics, palliative care, and primary care medicine. She has extensive experience working on studies related to aging populations, chronic disease management, and integrated care systems.
Before transitioning into medical writing, she practiced as a hospital-based internist and geriatrician, where she developed a strong interest in health systems research and patient-centered care frameworks. She is known for her ability to translate complex clinical and population-level data into clear, actionable scientific communication for diverse audiences.
Articles in this group — last 14 days
Meta-analysis evaluates high-intensity focused ultrasound for primary breast cancer treatment
Using ultrasound heat therapy to treat certain types of breast cancer
This meta-analysis examines the efficacy and safety of high-intensity focused ultrasound (HIFU) ablative therapy in patients with primary br…
A recent review shows how ultrasound heat therapy might help treat breast cancer without major surgery.
Systematic review and meta-analysis of AI for infant hip ultrasound accuracy
AI helps detect hip problems in babies during ultrasound exams
This meta-analysis of 9 studies evaluated AI-assisted ultrasound for developmental dysplasia of the hip in infants. Pooled sensitivity was 0…
A review of studies shows AI can accurately spot hip dysplasia in infants during ultrasounds, potentially helping non-experts.
Systematic review and meta-analysis on motor delay prevalence in children with craniosynostosis
Many young children with skull condition have motor delays before surgery
This systematic review and meta-analysis synthesized data on motor development delay in children with craniosynostosis. It found a preoperat…
A review of studies finds about one in three children with craniosynostosis has motor delays before surgery. This highlights the need for ea…
Meta-analysis finds 24% incidence of cognitive dysfunction after pediatric liver transplant
Nearly 1 in 4 kids face thinking problems after liver transplant
This meta-analysis of 7494 children after liver transplantation reports a pooled incidence of cognitive dysfunction of 24% (95% CI: 19.0%-30…
One in four children develops thinking problems after a liver transplant, with infants facing the highest risk.
Personalized diabetes texting with peer support improved glycemic control and remission rates in type 2 diabetes patients
Text Messages and Peer Support Can Help Reverse Type 2 Diabetes
This randomized controlled trial evaluated personalized diabetes texting combined with peer support education (DB-TEXT+ PSE) against standar…
Simple daily texts and group chats with others managing diabetes helped more people lower blood sugar and even reverse the condition compare…
Digital smoking cessation intervention for psychiatric inpatients shows preliminary abstinence benefits postdischarge
Digital tool helps psychiatric patients quit smoking after hospital
This randomized pilot trial enrolled 58 psychiatric inpatients who were tobacco users.
A new digital program helps psychiatric patients stay off cigarettes after leaving the hospital, when support usually drops off and relapse …
Network meta-analysis suggests mind-body exercises improve quality of life and function in chronic heart failure patients
1. HEADLINE
This network meta-analysis evaluated mind-body exercises like Yijinjing and meditation versus conventional care for patients with chronic he…
This mind-body exercise improves heart failure recovery better than
Systematic review and meta-analysis finds remote guidance increases exclusive breastfeeding rates
Remote guidance boosts exclusive breastfeeding rates for infants
This systematic review and meta-analysis of 8,389 infants found remote breastfeeding guidance significantly increased exclusive breastfeedin…
Text or phone guidance for new mothers significantly increased exclusive breastfeeding at 3 and 6 months, especially in less developed regio…
Scoping review shows WHO Access antibiotic susceptibility remains low in Pakistan clinical isolates
Pakistan's antibiotic resistance crisis threatens global health goals
This scoping review synthesizes data from 74 studies involving human clinical isolates in Pakistan.
Common infections in Pakistan are becoming harder to treat because most first-line antibiotics no longer work, threatening a key global heal…
Systematic review links reproductive concerns to mental health issues in 2,741 cancer patients
Cancer treatment often damages male fertility and causes deep anxiety
This systematic review synthesizes data from 2,741 reproductive-aged male patients with cancer regarding reproductive concerns.
Cancer therapy creates deep worry for men about fertility and mental health during recovery and beyond
MIRA feasibility study in Dutch long-term care organizations shows good reliability and high acceptability among professionals
Feasibility study finds MIRA approach works for long-term care innovation
This mixed-method cross-sectional feasibility study evaluated the Maastricht Innovation Readiness Approach (MIRA) in 10 Dutch long-term care…
A new feasibility study suggests the MIRA approach helps long-term care organizations assess their readiness for innovation through question…
Systematic review validates eDEM-CONNECTONTO ontology for dementia caregiver support tools
A new digital map helps caregivers understand dementia agitation
This systematic review evaluates the development and validation of the eDEM-CONNECTONTO ontology for dementia-related agitation.
A new digital tool maps how dementia agitation affects caregivers. This structured approach could help build better support systems for thos…
Zimberelimab plus lenvatinib showed immune rechallenge effects in 30 patients with advanced cervical cancer
Small trial finds immune rechallenge may help some advanced cervical cancer patients
This multicenter, single-arm, phase II trial evaluated combined zimberelimab and lenvatinib in 30 patients with advanced cervical cancer who…
A small study of 30 patients suggests combining zimberelimab and lenvatinib after prior treatment might help some with advanced cervical can…
UK trial reports 4-year event-free survival of 63% and overall survival of 68% in relapsed Wilms tumour patients
High-dose chemo plus stem cell rescue offers hope for relapsed Wilms tumour
This clinical trial report evaluates outcomes for 78 children with relapsed or refractory Wilms tumour treated in the United Kingdom.
A UK trial found that a risk-stratified protocol with high-dose melphalan and stem cell rescue helped some children with relapsed Wilms tumo…
Audiobooks with scaffolding improve vocabulary in elementary students
Audiobooks with coaching boost vocabulary in struggling readers
This 8-week RCT in 314 third- and fourth-graders found that text-supplemented audiobooks, especially with scaffolded support, improved book-…
Audiobooks alone didn't help poor readers. But with one-on-one coaching, they made real vocabulary gains.
Forgiveness psychoeducation reduces death anxiety and burden in end-of-life caregivers over one to three months
Forgiveness training eases death anxiety in caregivers
This randomized controlled trial involved 56 caregivers of patients at the end of life.
A small trial found that forgiveness training helped caregivers of dying patients feel less anxious and burdened.
Nurse and social worker telecare team intervention improved quality of life in high-risk patients with COPD, heart failure, or interstitial lung disease
Telecare Team Helps Heart And Lung Patients Feel Better For Less Cost
This randomized clinical trial evaluated a nurse and social worker telecare team intervention (ADAPT) in high-risk patients with chronic obs…
A simple phone call from a care team can significantly improve how patients feel and function while keeping costs low.
Early Supportive Care Reduces Symptom Burden in Phase I Cancer Trial Patients
Early Supportive Care Reduces Symptoms in Cancer Trial
This randomized controlled trial of 186 patients in Phase I cancer trials found that an Early Supportive Care program significantly reduced …
Patients receiving early supportive care alongside standard treatment reported significantly lower symptom burden and better psychosocial ne…
CBT-based psychoeducation improves anger control and death anxiety in cancer patients receiving chemotherapy
Eight CBT sessions help cancer patients control anger and fear of death
This randomized controlled trial enrolled 80 individuals receiving chemotherapy, with 40 in the control group and 40 receiving eight session…
Eight sessions of CBT-based psychoeducation significantly improved anger control and reduced death anxiety in people receiving chemotherapy …
Multiple gender expressions in anti-smoking messages reduced perceived effectiveness among sexual and gender minority young adults
Anti-smoking ads with multiple gender expressions lowered perceived effectiveness in SGM young adults
This randomized online experiment involved 1,113 sexual and gender minority young adults.
Ads showing multiple gender expressions were less effective than those showing masculine expressions among sexual and gender minority young …
Statistical framing increased screening intentions while narrative framing increased information-seeking in autism spectrum disorder
Statistical messages boost autism screening intentions
This randomized experiment examined how message type and framing affect behavioral intentions regarding autism spectrum disorder screening.
Numbers may persuade parents to screen for autism, but stories drive information-seeking.
Text messaging plus educational materials improves healthy eating in uncontrolled diabetes
Text Messages Plus Education Improve Healthy Eating in Diabetes Care
This three-arm pragmatic randomized trial in 666 African-American adults with uncontrolled diabetes found that adding text messaging to educ…
A trial found that adding text messages to diabetes education helped participants eat healthier more often than education alone.
Video and plaque disclosing tablets improved oral hygiene indices in adult orthodontic patients compared to verbal instructions alone
Verbal instructions may be enough for orthodontic patients to improve oral hygiene
This open label randomised controlled trial enrolled 96 participants randomised to receive video, plaque disclosing tablets, or verbal instr…
A trial of 96 adult orthodontic patients found that simple verbal instructions improved oral hygiene just as well as video or plaque tablets…
Nutrition Info front-of-package labels improve consumer understanding in online trial
Simple nutrition labels help shoppers pick healthier food options
In an online randomized experiment with 5,636 U.S.
New front-of-package labels improved how shoppers identify healthy food. The Nutrition Info label led to the biggest gains in understanding.
Chatbot plus brochures did not improve cataract knowledge or anxiety vs brochures alone
A Chatbot Fails to Beat Brochures for Cataract Info
This pilot randomized controlled trial of 64 cataract surgery patients compared standard brochures plus a hospital-specific chatbot (Mina) t…
A new chatbot for cataract surgery patients did not teach them more than simple brochures and struggled with older users.
Facebook campaign boosts awareness but not school meal uptake in children
Facebook campaigns did not increase childrens school meal participation
This RCT of 832 parents in states with universal free school meals found that a 6-week Facebook campaign increased awareness of school meals…
A six-week Facebook campaign for parents did not increase childrens school lunch or breakfast eating despite higher message engagement.
Educational video improves spirometry success in preschool children
Short Video Boosts Spirometry Success in Preschoolers
This randomized controlled trial in 132 preschool children found that watching a short educational video before spirometry significantly imp…
A short educational video helped 84% of preschoolers complete a lung test successfully, compared to 66% with standard instructions.
Mental health information and diagnosis reduced guilt ratings in mock criminal trial participants
More mental health details in court lowered guilt ratings for those with higher knowledge
This randomized controlled trial involved 243 mock criminal trial participants.
Adding mental health details and diagnoses to a case reduced guilt ratings, especially for people who understand these conditions better.
Virtual Reality methods improved reproductive health and family planning attitudes in women compared to face-to-face training
Virtual reality training boosts family planning attitudes in women
This randomized controlled trial enrolled 120 patients across three groups to evaluate Virtual Reality methods for reproductive health and f…
A new trial shows virtual reality methods significantly improve reproductive health attitudes compared to standard face-to-face training for…
Disaster education boosts preparedness in Turkish women, randomized trial finds
Disaster education boosts preparedness in women in western Turkey
This randomized controlled trial in 120 women in western Turkey found that a structured disaster awareness program significantly improved di…
A four-week course on disaster types and first aid significantly improved awareness and preparedness scores in women compared to a nutrition…
Motivational Interviewing Program Reduces Digital Game Addiction and Cyberbullying in Adolescents
Motivational Interviewing Cuts Digital Game Addiction in Teens
This randomized controlled trial in 52 ninth-grade adolescents from a single high school in Türkiye found that a motivational interviewing-s…
A brief program using motivational interviewing reduced digital game addiction and cyberbullying in ninth graders.
Systematic review finds online cleft care materials exceed recommended readability levels
Cleft lip and palate online materials too complex for caregivers
This systematic review and meta-analysis evaluated nine studies on online patient education materials for cleft care.
Online health materials for cleft lip and palate are written at reading levels too high for most caregivers, a new analysis finds.
Same-day discharge after G-POEM for gastroparesis shows no difference in readmission rates
Same-day discharge after G-POEM shows shorter procedure time without more readmissions
This systematic review and meta-analysis compared same-day discharge (SDD) versus overnight admission after G-POEM for gastroparesis.
A new analysis finds patients can go home the same day after G-POEM surgery with fewer complications and no higher risk of returning to the …
Primary community health care nurses improve patient outcomes and reduce costs compared to medical practitioners
Meta-analysis shows primary care nurses improve health and save money compared to medical practitioners
This meta-analysis pooled data from 14,523 participants in primary community health care settings.
A large analysis of 14,523 people found primary care nurses improved patient health and reduced costs compared to medical practitioners.
Hybrid NLP and LLM system extracts deprescribing recommendations from electronic health records for older hospitalized patients
New tool helps doctors stop unnecessary drugs for older hospital patients
This retrospective cohort study evaluated a two-stage hybrid system combining rule-based natural language processing and open-source large l…
A new computer system accurately finds advice to stop antibiotics and painkillers for older adults. This helps hospitals reduce risky medici…
Acupuncture combined with Baduanjin improves muscle mass and function in older adults with sarcopenia
Combination therapy improves muscle mass in older adults with sarcopenia
This randomized controlled trial enrolled 105 adults aged 60 to 84 years with sarcopenia at Nanjing Hospital of Traditional Chinese Medicine…
A 12-week trial found that combining acupuncture with Baduanjin exercise improved muscle mass and physical function more than either treatme…
Systematic review and meta-analysis of digital-based exercise interventions for older adults
Digital exercise helps older adults feel more confident and move better
This systematic review and meta-analysis evaluated digital-based exercise interventions in older adults.
Digital exercise programs improved how older adults move and balance, but did not change their fear of falling in this large review.
Therapeutic Touch Reduces Crying and Improves Sleep in Infants With Colic
Therapeutic touch reduces crying in babies with colic
This randomized controlled trial in 96 infants with colic found that therapeutic touch based on Watson's Human Care Theory significantly red…
A new trial shows gentle therapeutic touch helps babies cry less and sleep better when they have infantile colic.
Mycophenolate mofetil non-inferior to prednisone for first-episode nephrotic syndrome in children
Mycophenolate Mofetil Offers Alternative to Steroids for Nephrotic Syndrome
This phase 3 non-inferiority trial randomized 272 children aged 1-10 years with first-episode steroid-sensitive nephrotic syndrome to mycoph…
A new trial shows mycophenolate mofetil works as well as prednisone for children with nephrotic syndrome, with fewer steroid side effects.
AquOTic water competency intervention improves outcomes in children with autism
Water therapy improves skills for children with autism spectrum disorder
This pre-post cohort study of 37 children with autism ages 5 to 9 found that a 10-week occupational therapy-based water competency intervent…
A water-based occupational therapy program significantly improved performance and satisfaction scores in children with autism spectrum disor…
Play-based cognitive flexibility training boosts creativity in third graders
Playful workshops boost story skills and flexible thinking for third graders
This RCT in 249 third graders found that a 14-session play-based workshop significantly improved narrative creativity and cognitive flexibil…
A fun 14-session workshop helped third graders write better stories and think more flexibly than peers in regular classes.
Adenotonsillectomy with turbinate ablation shows no added benefit for pediatric SDB
Submucosal ablation adds little benefit to adenotonsillectomy for children
This randomized prospective study compared adenotonsillectomy with submucosal ablation of turbinates (AT with SAT) versus AT alone in 51 chi…
A small study found no significant difference in nasal quality of life between children receiving adenotonsillectomy alone versus those also…
Operating microscope use increased operative time in cleft palate repair for infants under two years
Microscope use improves vision but takes longer for new surgeons
This prospective, quasi-randomized controlled study evaluated operating microscope use versus surgical loupe use in 40 patients under two ye…
New tools give surgeons a clearer view during cleft palate repairs, though the learning curve means operations take longer at first.
Enhanced face-washing intervention increases soap use in trachoma-endemic Ethiopia
Free wash stations helped families in Ethiopia wash faces with soap more often
This cluster-randomised trial in 204 Ethiopian households found that an enhanced face-washing intervention increased face-washing prevalence…
A new program in Ethiopia gave families free wash stations and taught them to use soap. This simple change boosted face washing rates among …
Infant formula with dairy lipids showed no difference in fat mass compared to control formula or exclusive breastfeeding
Infant formula with dairy lipids shows no difference in fat mass compared to control
This randomized, controlled, double-blind trial compared a formula enriched with dairy lipids to a control formula and exclusive breastfeedi…
A trial of 249 infants found that a formula with dairy lipids did not change body fat compared to standard formula or breastfeeding.
Nicotinamide Riboside Plus Exercise Improves Fitness in Friedreich's Ataxia
Combining exercise and nicotinamide riboside improved fitness in Friedreich's ataxia patients
This phase 2 randomized trial in 66 individuals with Friedreich's ataxia found that 12 weeks of nicotinamide riboside plus exercise increase…
A 12-week trial found that combining exercise with nicotinamide riboside improved heart and lung fitness in people with Friedreich's ataxia.
Combined low-level laser and ultrasound therapy showed possible efficacy and safety for growing pains in children over 30 days
New therapy may ease growing pains without using medicine
This pilot randomized controlled trial evaluated combined low-level laser and ultrasound therapy versus placebo in children aged four to twe…
A new treatment using light and sound waves could help children stop hurting without taking pills
Systematic review and meta-analysis of canonical babbling ratio trajectories in infants aged 5 to 24 months across 42 studies
Babbling grows steadily from five to twenty-four months in babies everywhere
This systematic review and meta-analysis examined canonical babbling ratio (CBR) measurement across 42 studies involving 1277 infants aged 5…
A large review found that babies babble more as they age, with interactive play sessions capturing more sounds than quiet home recordings.
Meta-analysis shows moderate positive learning effects from physically embodied educational robots in classrooms
Classroom Robots Boost Children's Learning, Review Finds
This meta-analysis reviews evidence on the impact of physically embodied educational robots (PERs) on learning outcomes in children.
A review of 3665 children finds that physically embodied educational robots moderately improve learning outcomes.
Systematic review meta-analysis shows higher complication rates in young children undergoing tonsillectomy
Young kids under three can safely go home after tonsil surgery
This systematic review and meta-analysis evaluated complications of tonsillectomy or adenotonsillectomy in children aged 2 to 3 years compar…
New research shows toddlers aged two to three can likely go home the same day after having their tonsils removed without extra risk.
Systematic review and meta-analysis supports adalimumab plus methotrexate for JIA-associated uveitis
Combination therapy reduces relapse risk in children with eye inflammation from arthritis
This systematic review and meta-analysis of RCTs evaluated adalimumab plus methotrexate in children with juvenile idiopathic arthritis-assoc…
Combining adalimumab with methotrexate lowers relapse risk and helps reduce steroid use in children with arthritis-related eye inflammation.
Meta-analysis shows Mycoplasma pneumoniae prevalence in children varied before, during, and after COVID-19
Mycoplasma pneumoniae infections in children rose sharply after the pandemic ended
This systematic review and meta-analysis of 70 studies examined M.
A review of 70 studies shows infection rates in kids jumped significantly after the pandemic, while rates stayed low during the outbreak.
Meta-analysis shows integrated nursing interventions improve outcomes in paediatric severe pneumonia
Integrated nursing care improves severe pneumonia in children
This meta-analysis reviews six studies conducted in paediatric intensive care units involving paediatric patients with severe pneumonia.
A review of six studies finds that integrated nursing care helps children with severe pneumonia recover faster, with less fever and shorter …
SBRT plus atezolizumab shows activity in metastatic cervical cancer
Radiation plus immune therapy helps some patients with advanced cervical cancer survive longer
This prospective phase II trial evaluated SBRT followed by atezolizumab in 21 patients with metastatic, recurrent, or persistent cervical ca…
A small trial found that adding immune therapy to radiation helped some patients with advanced cervical cancer keep their disease stable for…
In-person group sessions boost fruit/vegetable intake in Latina breast cancer survivors
In-Person Sessions Boost Fruit and Vegetable Intake in Latina Breast Cancer Survivors
This randomized factorial trial in 167 Latina breast cancer survivors found that in-person group sessions increased daily fruit/vegetable in…
In-person group sessions helped Latina breast cancer survivors eat more fruits and vegetables, while the control group's intake dropped shar…
Capivasertib-paclitaxel fails to improve overall survival in metastatic TNBC
New drug combo did not extend life for metastatic triple-negative breast cancer patients in this trial
This phase III RCT in 812 patients with previously untreated metastatic triple-negative breast cancer found that adding capivasertib to pacl…
A large global trial found that adding capivasertib to paclitaxel did not improve overall survival for patients with metastatic triple-negat…
Contrast-enhanced mammography reduces costs per QALY in breast cancer screening recalls compared to conventional imaging
Contrast-enhanced mammography may cut costs for breast cancer screening
This RCT evaluated women recalled from breast cancer screening in a hospital setting.
Using contrast-enhanced mammography as the first test for women recalled from screening could lower imaging costs without harming quality of…
Tandem-ring applicator lowers rectal and sigmoid doses compared to tandem-ovoid in cervical cancer patients
New applicator lowers radiation to rectum in cervical cancer treatment
This randomized controlled trial enrolled 36 eligible patients who completed pelvic external beam radiotherapy.
A small trial found a tandem-ring applicator reduced radiation dose to the rectum and sigmoid colon compared to a tandem-ovoid device during…
Higher shoulder joint radiation dose linked to worse arm morbidity in breast cancer patients with SLN macrometastases
High radiation doses to the shoulder may cause long-term arm pain in breast cancer patients
This randomized trial evaluated 868 patients with breast cancer and 1-2 sentinel lymph node macrometastases in a Swedish setting.
New data shows that higher radiation doses near the shoulder joint can lead to lasting arm pain and stiffness in breast cancer survivors
Systematic review of post-traumatic growth in 6382 breast cancer patients
Post-traumatic growth is common among breast cancer survivors and linked to better coping
This systematic review and meta-analysis examines post-traumatic growth (PTG) among 6382 breast cancer patients.
A large review finds post-traumatic growth is nearly universal in breast cancer survivors and connects to lower distress and stronger resili…