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Anesthesiology & Pain Medicine
RCT
Intranasal naloxone reverses opioid-induced respiratory depression in opioid-naive and daily users within 2 to 17 minutes
Narcan nasal spray reverses opioid breathing depression quickly
This prospective crossover trial enrolled 12 opioid-naive individuals and 18 daily opioid users.
Narcan nasal spray restored breathing within minutes in opioid users, but some had delayed or incomplete recovery.
May 1, 2026
Anesthesiology & Pain Medicine
RCT
Feedback-regulated background infusion reduces postoperative nausea and vomiting in laparoscopic myomectomy patients
Smart pump cuts nausea after surgery without hurting pain control
This randomized controlled trial enrolled 132 patients undergoing laparoscopic myomectomy.
A new smart pain pump adjusts medicine automatically to cut nausea after surgery while keeping pain relief strong for patients who need it m…
Apr 29, 2026
Rheumatology
RCT
Oxycodone PCIA reduces visceral pain vs. sufentanil after repeat cesarean section
Better Pain Relief Found for Women After Repeat C-Section
This randomized controlled trial in 100 women undergoing elective repeat cesarean section compared patient-controlled intravenous analgesia …
A new study shows a specific painkiller might work better for women having repeat C-sections.
Frontiers
Apr 23, 2026
Cardiology
RCT
Maternal voice intervention effects on sleep in children with congenital heart disease undergoing open-heart surgery remain unreported in this protocol
Imagine your child is in the hospital after major heart surgery. Machines beep. Lights stay on. It’s a stressful place to rest, let alone sleep deeply. But what if the most powerful tool for healing wasn't a new machine, but a sound they've known since before they were born?
This randomized controlled trial protocol investigates the effect of a maternal voice-based auditory intervention on sleep efficiency in chi…
For a child in intensive care, better sleep isn't just about rest—it could be a key part of physical recovery.
Frontiers
Apr 10, 2026
Anesthesiology & Pain Medicine
RCT
Oliceridine PCA non-inferior to sufentanil for knee arthroplasty pain, with lower nausea and vomiting
Oliceridine shows similar pain relief to sufentanil after knee surgery with fewer side effects
A randomized controlled trial in 138 elderly patients undergoing knee arthroplasty found Oliceridine patient-controlled analgesia was non-in…
Oliceridine works as well as sufentanil for knee surgery pain but causes less nausea and vomiting in elderly patients.
Apr 6, 2026