Fecal microbiota transplantation shows efficacy for recurrent C. difficile infection, IBD, and autism spectrum disorder in children
A Gut Reset Treatment Is Helping Sick Kids Bounce Back
This systematic review and meta-analysis of 47 studies evaluated fecal microbiota transplantation (FMT) in children with recurrent C.
A gut bacteria transplant helps children with stubborn infections, bowel disease, and autism symptoms, though kids with IBD face more side e…
7-Day Antibiotic Regimen Non-Inferior to 14-Day for Uncomplicated Neonatal Sepsis in RCT
Can shorter antibiotics cure newborn sepsis just as well as two weeks of treatment?
This randomized control assessor-blinded trial evaluated 140 neonates weighing ≥ 1000 g with culture-positive sepsis in a tertiary Neonatal …
A 7-day antibiotic course for newborn sepsis worked as well as 14 days, with babies leaving the hospital sooner and needing less breathing s…
Infliximab in IVIG-resistant Kawasaki disease with cholestatic hepatitis: case report
Can a new drug stop heart damage in Kawasaki disease when standard treatments fail?
A case report describes a 2-year-old Han Chinese male with IVIG-resistant Kawasaki disease and cholestatic hepatitis treated with infliximab…
In a two-year-old boy with Kawasaki disease, the drug infliximab quickly stopped his fever and liver trouble, yet his heart artery damage ke…
Adding visual biofeedback to motor-based speech therapy improves /ɹ/ generalization in children with RSSD
Can adding visual feedback help children master difficult speech sounds they haven't practiced yet?
This randomized controlled trial enrolled 108 children aged 9-15 years with residual speech sound disorder affecting American English /ɹ/.
Adding visual feedback during speech therapy helps children master new sounds better than standard treatment alone, with ultrasound showing …
PLEKHA6 variants identified in 24 patients with idiopathic hypogonadotropic hypogonadism across two cohorts
Scientists found a new gene linked to a rare condition that stops puberty in young people
This cohort study examined 1,822 patients with idiopathic hypogonadotropic hypogonadism (IHH) to identify genetic causes.
A broken gene stops puberty by blocking a key hormone in the brain, explaining why some young people never start developing.
Expert review outlines diagnostic and therapeutic management strategies for eosinophilic granulomatosis with polyangiitis
Rare Lung and Blood Disease Gets a Smarter Treatment Map
This expert review addresses the management of patients with eosinophilic granulomatosis with polyangiitis (EGPA), focusing on glucocorticoi…
A new expert roadmap shifts treatment for rare EGPA disease from steroids to targeted biologic drugs for patients with stubborn asthma and o…
Review of a case report on necrotizing laryngotracheobronchitis after Mycoplasma pneumoniae pneumonia
Could a common infection trigger a rare, severe throat condition in a young boy?
This review summarizes a case report of a 7-year-old boy with necrotizing laryngotracheobronchitis following Mycoplasma pneumoniae pneumonia…
A common respiratory bug turned a seven-year-old boy's throat infection into a rare, severe condition requiring multiple airway washes to re…
Systematic review identifies community-based strategies that improve diversity in pediatric research recruitment
Tailored recruitment strategies improve diversity in pediatric research studies
This systematic review of 23 studies (5,482 pediatric participants aged 0.55–19.8 years) evaluated recruitment and retention strategies aime…
Community-based recruitment and flexible scheduling help bring more diverse children and parents into pediatric research studies.
Case Report Review Synthesis: Cyclic Neutropenia Response to rhG-CSF in a Pediatric Patient
A young girl with rare blood cycles found hope in a specific growth factor treatment
This publication presents a case report and synthesis regarding cyclic neutropenia management in children.
A seven-year-old girl with rare cyclic neutropenia found safety from dangerous infection cycles using growth factor treatment and careful ca…
Retrospective cohort identifies TIBC and rPLR cutoffs for EBV-IM-related hepatic injury in children
Iron Levels and Blood Counts Predict Liver Trouble in Kids with Mono
This retrospective cohort study of 52 propensity-matched children with EBV-associated infectious mononucleosis found that a TIBC cutoff of 5…
High iron levels and low platelet-to-lymphocyte ratios signal liver trouble in kids with mono before standard tests show it.
Acyclovir treatment for HSV in febrile hospitalized children at Jinan Children's Hospital
The hidden troublemaker
This retrospective cohort study evaluated 100 febrile hospitalized children at Jinan Children's Hospital.
Finding a second germ alongside Herpes Simplex Virus in sick children explains why some stay hospitalized longer than expected.
Retrospective cohort study links prenatal and neonatal factors to cPVL in preterm infants
Could early brain monitoring help predict severe brain injury in premature babies?
This retrospective cohort study examined 46 preterm infants to assess the association between various clinical parameters and cerebral periv…
A study found that early brain blood flow measurements link to severe brain injury in premature babies, offering potential clues for future …